Evidence map›Paper›PMID 42566432›Full record

ArticlePloS one2026

Uncovering complex correlations between multidimensional factors and breastfeeding duration using XGBoost.

Lijing Yang, Wanju Wang, Yajuan Chen

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In one paragraph

Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Lijing YangDepartment of Obstetrics and Gynecology, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei, China.ORCID 0009-0003-7733-5896
Wanju WangDepartment of Obstetrics and Gynecology, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei, China.
Yajuan ChenDepartment of Obstetrics and Gynecology, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBreastfeeding duration is influenced by a complex interplay of obstetric, physiological, and sociodemographic factors. Traditional linear statistical models often struggle to capture the high-dimensional, non-linear synergistic effects among these variables, while complex deep learning models are prone to overfitting on small clinical datasets.

methodsTo address these challenges, this study proposes an interpretable machine learning framework based on eXtreme Gradient Boosting (XGBoost). We analyzed clinical follow-up data from 210 postpartum women. The framework incorporates Explicit Polynomial Feature Engineering to construct high-order interaction terms and utilizes SMOTE to resolve class imbalance. Crucially, SHAP (SHapley Additive exPlanations) analysis was employed to provide bidirectional feature attribution. Results: The proposed model achieved robust, cross-validated performance with an Accuracy of 76.2% (95% CI: 64.3%-88.1%), an AUC of 0.72 (95% CI: 0.54-0.89), and a high Recall of 0.92 for the long-term breastfeeding group (≥ 11 months), outperforming traditional baselines. SHAP analysis identified critical non-linear risk patterns. Notably, the interaction between "Delivery Mode × Milk Stasis Duration" demonstrated that the protective effect of vaginal delivery mitigates stasis risks, whereas Cesarean sections disproportionately amplify the inhibitory effect of milk stasis. Additionally, the negative interaction of "Education × Feeding Type" highlighted the compounded risk for highly educated mothers transitioning to mixed feeding.

conclusionsThis study confirms that an interpretable XGBoost framework with explicit interaction features effectively overcomes the modeling bottlenecks of small-sample clinical data. By uncovering hidden synergistic risk factors, it provides a data-driven basis for precision lactation support, advocating for targeted interventions for specific high-risk profiles rather than generic education.

Indexed as

Breast FeedingAdultBoosting Machine Learning AlgorithmsFemaleHumansMachine LearningPredictive Learning ModelsTime Factors

Identifiers

PMID42566432
PMCPMC13450716

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.