ArticlePloS one2026
Uncovering complex correlations between multidimensional factors and breastfeeding duration using XGBoost.
Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBreastfeeding duration is influenced by a complex interplay of obstetric, physiological, and sociodemographic factors. Traditional linear statistical models often struggle to capture the high-dimensional, non-linear synergistic effects among these variables, while complex deep learning models are prone to overfitting on small clinical datasets.
methodsTo address these challenges, this study proposes an interpretable machine learning framework based on eXtreme Gradient Boosting (XGBoost). We analyzed clinical follow-up data from 210 postpartum women. The framework incorporates Explicit Polynomial Feature Engineering to construct high-order interaction terms and utilizes SMOTE to resolve class imbalance. Crucially, SHAP (SHapley Additive exPlanations) analysis was employed to provide bidirectional feature attribution. Results: The proposed model achieved robust, cross-validated performance with an Accuracy of 76.2% (95% CI: 64.3%-88.1%), an AUC of 0.72 (95% CI: 0.54-0.89), and a high Recall of 0.92 for the long-term breastfeeding group (≥ 11 months), outperforming traditional baselines. SHAP analysis identified critical non-linear risk patterns. Notably, the interaction between "Delivery Mode × Milk Stasis Duration" demonstrated that the protective effect of vaginal delivery mitigates stasis risks, whereas Cesarean sections disproportionately amplify the inhibitory effect of milk stasis. Additionally, the negative interaction of "Education × Feeding Type" highlighted the compounded risk for highly educated mothers transitioning to mixed feeding.
conclusionsThis study confirms that an interpretable XGBoost framework with explicit interaction features effectively overcomes the modeling bottlenecks of small-sample clinical data. By uncovering hidden synergistic risk factors, it provides a data-driven basis for precision lactation support, advocating for targeted interventions for specific high-risk profiles rather than generic education.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.