Evidence map›Paper›PMID 42566178›Full record

ArticleGeneral thoracic and cardiovascular surgery2026

The geriatric 8 score as a predictor of postoperative outcomes in elderly patients undergoing esophagectomy.

Naoki Takahashi, Akihiko Okamura, Taro Shiga, Ken Shimizu, Keisho Chin, Shota Fukuoka, Kumi Takagi, Misuzu Ishii, Jun Kanamori, Masayuki Watanabe

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Article in General thoracic and cardiovascular surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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10 authors.

Naoki TakahashiDepartment of Esophageal Surgery, Cancer Institute Hospital, Japanese Foundation for Cancer Research, 3-8-31 Ariake, Koto-ku, Tokyo, 135-8550, Japan.
Akihiko OkamuraDepartment of Esophageal Surgery, Cancer Institute Hospital, Japanese Foundation for Cancer Research, 3-8-31 Ariake, Koto-ku, Tokyo, 135-8550, Japan. akihiko.okamura@jfcr.or.jp.ORCID http://orcid.org/0000-0002-3217-8888
Taro ShigaDepartment of Onco-Cardiology/Cardiovascular Medicine, Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan.
Ken ShimizuDepartment of Psycho-Oncology, Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan.
Keisho ChinDepartment of Gastrointestinal Medical Oncology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan.
Shota FukuokaDepartment of Gastrointestinal Medical Oncology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan.
Kumi TakagiDepartment of Clinical Nutrition, Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan.
Misuzu IshiiDepartment of Clinical Nutrition, Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan.
Jun KanamoriDepartment of Esophageal Surgery, Cancer Institute Hospital, Japanese Foundation for Cancer Research, 3-8-31 Ariake, Koto-ku, Tokyo, 135-8550, Japan.
Masayuki WatanabeDepartment of Esophageal Surgery, Cancer Institute Hospital, Japanese Foundation for Cancer Research, 3-8-31 Ariake, Koto-ku, Tokyo, 135-8550, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Geriatric 8 (G8) screening tool is widely used to assess frailty in elderly patients with cancer. However, its significance in patients undergoing esophagectomy remains unclear. This study aimed to evaluate the association between preoperative G8 scores and postoperative outcomes in elderly patients who underwent esophagectomy for esophageal cancer.

methodsThis study retrospectively analyzed 130 patients aged ≥ 65 years who underwent esophagectomy for esophageal cancer. The patients were classified into tertiles (low, medium, and high) based on their G8 scores. Postoperative and survival outcomes were compared, and multivariable logistic regression analysis was used to assess the association between G8 scores and postoperative outcomes.

resultsThe median G8 score was 13 (interquartile range (IQR): 11.5-15). Postoperatively, severe complications occurred in 23.8%, reoperation in 6.9%, and readmission in 12.3% of patients. The median length of hospital stay was 17 days (IQR: 14-25 days). Patients with lower G8 scores had significantly higher rates of severe complications, reoperation, prolonged hospitalization, and readmission (all P < 0.05). G8 score showed a significant inverse association with severe complications (adjusted odds ratio 0.73, 95% confidence interval, 0.59-0.88, P < 0.001). Patients with lower G8 scores were significantly less likely to receive systemic chemotherapy after disease recurrence (P = 0.017) and their overall survival was unfavorable (P = 0.046).

conclusionsLower preoperative G8 scores were associated with higher rates of severe complications, reoperation, prolonged hospitalization, and readmission. The G8 screening tool helps to predict postoperative outcomes in elderly patients undergoing esophagectomy for esophageal cancer.

Indexed as

ComplicationsEsophageal cancerEsophagectomyGeriatric 8Geriatric assessment

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.