Evidence map›Paper›PMID 42566126›Full record

ArticleMedical oncology (Northwood, London, England)2026

Iron oxide nanoparticles co-conjugated with hyaluronic acid and limonene trigger oxidative stress and cell cycle arrest in triple-negative breast cancer.

Bahareh Ahang, Hadi Habibollahi, Ali Salehzadeh, Masoud Mokhtary

Abstract read
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Article in Medical oncology (Northwood, London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bahareh AhangDepartment of Biology, Ra.C., Islamic Azad University, Rasht, Iran.
Hadi HabibollahiDepartment of Biology, Ra.C., Islamic Azad University, Rasht, Iran. ha.habibollahi@iau.ac.ir.
Ali SalehzadehDepartment of Biology, Ra.C., Islamic Azad University, Rasht, Iran.
Masoud MokhtaryDepartment of Chemistry, Ra.C., Islamic Azad University, Rasht, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The hyaluronic acid receptor is typically overexpressed in cancer cells, and hyaluronic acid targeting has gained attention in cancer treatment. In this work, cytotoxic potential of magnetic iron oxide nanoparticles co-conjugated with hyaluronic acid and limonene in the MDA-MB-231 cell line was characterized. Physicochemical characteristics of the nanoparticles were studied by FT-IR, XRD, TEM, SEM-EDS, DLS, zeta potential and VSM analyses. Cytotoxic effects of Fe

Indexed as

Cell Cycle CheckpointsHyaluronic AcidLimoneneMagnetic Iron Oxide NanoparticlesOxidative StressTriple Negative Breast NeoplasmsApoptosisCell Line, TumorFemaleFerric CompoundsHumansMDA-MB-231 CellsReactive Oxygen SpeciesFerric CompoundsHyaluronic AcidLimoneneReactive Oxygen SpeciesBreast cancerHyaluronic acidLimoneneMagnetic iron oxide nanoparticlesTriple-negative breast cancer (TNBC)

Identifiers

PMID42566126

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.