Evidence map›Paper›PMID 42566101›Full record

ArticleHernia : the journal of hernias and abdominal wall surgery2026

Diagnostic value of shear wave elastography in assessing the effectiveness of preoperative botulinum toxin type A therapy in patients with postoperative ventral hernias W3.

R S Rajabzoda, A V Protasov, O I Mazurova

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Article in Hernia : the journal of hernias and abdominal wall surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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3 authors.

R S RajabzodaDepartment of Operative Surgery and Clinical Anatomy named after I.D. Kirpatovsky, Peoples Friendship University of Russia named after Patrice Lumumba, Moscow, Russian Federation. ruxshona19111999@mail.ru.ORCID http://orcid.org/0009-0007-3369-3818
A V ProtasovDepartment of Operative Surgery and Clinical Anatomy named after I.D. Kirpatovsky, Peoples Friendship University of Russia named after Patrice Lumumba, Moscow, Russian Federation.ORCID http://orcid.org/0000-0001-5439-9262
O I MazurovaDepartment of Operative Surgery and Clinical Anatomy named after I.D. Kirpatovsky, Peoples Friendship University of Russia named after Patrice Lumumba, Moscow, Russian Federation.ORCID http://orcid.org/0000-0003-2677-6272

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No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionComplex W3 ventral hernias with loss of domain (LOD) pose challenges in abdominal wall reconstruction due to pathological retraction and increased stiffness of the lateral abdominal muscles. Preoperative botulinum toxin type A (BTA) facilitates tension-free closure, but objective assessment remains poorly standardized. Two-dimensional shear wave elastography (2D-SWE) enables non-invasive quantification of tissue stiffness.

methodsThis prospective study included 20 healthy volunteers (control) and 6 patients with EHS W3 ventral hernias. Reference stiffness values for external oblique (EO), internal oblique (IO), and transversus abdominis (TrA) were established using 2D-SWE. Patients underwent stiffness measurements before BTA, one month after BTA, and at 1,3,6,12 months postoperatively. All underwent Rives-Stoppa hernioplasty.

resultsControl reference values were 13.38 kPa (EO), 13.61 kPa (IO), and 15.23 kPa (TrA). Before BTA, hernia patients showed elevated EO (24.2 ± 4.8) and IO (20.6 ± 2.3) stiffness (p < 0.001), while TrA stiffness (17.8 ± 3.6) did not differ from controls (p = 0.09). One month after BTA, stiffness decreased (EO: 14.3 ± 2.4, p = 0.21 vs. controls; IO: 10.2 ± 1.8, p < 0.001; TrA: 9.6 ± 1.2, p < 0.001). Postoperative stiffness progressively declined through 12 months (EO: 7.8 ± 0.9; IO: 7.4 ± 0.8; TrA: 7.3 ± 0.4). Primary fascial closure was achieved in all patients without additional component separation.

conclusions2D-SWE provides objective assessment of BTA-induced muscular relaxation and postoperative remodeling. Established control reference values enable reliable stratification of pathological stiffness and monitoring of therapeutic response, supporting personalized surgical planning.

Indexed as

Abdominal MusclesBotulinum Toxins, Type AElasticity Imaging TechniquesHernia, VentralHerniorrhaphyNeuromuscular AgentsAdultAgedCase-Control StudiesFemaleHumansMaleMiddle AgedPreoperative CareProspective StudiesTreatment OutcomeBotulinum Toxins, Type ANeuromuscular Agents2D-SWEAbdominal wall musclesBotulinum toxin type APostoperative ventral herniaShear wave elastography

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.