Evidence map›Paper›PMID 42565928›Full record

ArticleJournal of echocardiography2026

Change in the prognostic utility of regional left ventricular longitudinal strain values in patients undergoing transcatheter aortic valve implantation.

Hiroki Usuku, Eiichiro Yamamoto, Mikuri Ryu, Ryudai Higashi, Atsushi Nozuhara, Fumi Oike, Yuichiro Shirahama, Kyoko Hirakawa, Masanobu Ishii, Shinsuke Hanatani and 7 more

Abstract read
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Article in Journal of echocardiography, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors.

Hiroki UsukuDepartment of Laboratory Medicine, Kumamoto University Hospital, Kumamoto, Japan.ORCID http://orcid.org/0000-0003-4086-7541
Eiichiro YamamotoDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556, Japan. eyamamo@kumamoto-u.ac.jp.
Mikuri RyuDepartment of Laboratory Medicine, Kumamoto University Hospital, Kumamoto, Japan.
Ryudai HigashiDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556, Japan.
Atsushi NozuharaDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556, Japan.
Fumi OikeDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556, Japan.
Yuichiro ShirahamaDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556, Japan.
Kyoko HirakawaDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556, Japan.
Masanobu IshiiDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556, Japan.
Shinsuke HanataniDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556, Japan.
Tadashi HoshiyamaDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556, Japan.
Hisanori KanazawaDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556, Japan.
Yuichiro ArimaDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556, Japan.
Hiroaki KawanoDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556, Japan.
Yasuhiro IzumiyaDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556, Japan.
Yasuhito TanakaDepartment of Laboratory Medicine, Kumamoto University Hospital, Kumamoto, Japan.
Kenichi TsujitaDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo evaluate the difference in prognostic utility of echocardiographic parameters between pre- and post-transcatheter aortic valve implantation (TAVI) periods. METHODS AND

resultsThis study enrolled 189 patients who underwent TAVI at Kumamoto University Hospital between 2015 and 2023 and had available echocardiographic data for the pre- and post-TAVI periods. Thirty-seven deaths occurred within the follow-up period (median 574 [357-934] days after post-TAVI period). Apical longitudinal strain (LS) in the pre- and post-TAVI periods and mid LS in the post-TAVI period were significantly associated with all-cause death after adjusting for various factors (pre-TAVI apical LS, hazard ratio [HR] 0.92, 95% confidence interval [CI] 0.85-0.99, p<0.05; post-TAVI apical LS, HR 0.88, 95%CI 0.82-0.95, p<0.01; post-TAVI mid LS, HR 0.87, 95%CI 0.78-0.97, p<0.05). Receiver operating characteristics analysis showed that the area under the curve for mid LS was significantly higher post-TAVI than pre-TAVI (0.65 vs. 0.54, p<0.05). For prediction of all-cause death, the optimal post-TAVI cutoff value for mid LS was 12.5% (sensitivity 75%, specificity 51%). Kaplan-Meier survival analysis revealed significantly higher all-cause mortality in patients with low mid LS (<12.5%) than in those with high mid LS (≥12.5%) (p<0.01, log-rank test).

conclusionPre-TAVI apical LS was an important prognostic factor in patients undergoing TAVI. In contrast, mid LS and apical LS were significant prognostic factors in the post-TAVI period, indicating a change in the prognostic significance of left ventricular longitudinal strain parameters according to the timepoint in the TAVI procedure.

Indexed as

2D speckle tracking echocardiographyAortic stenosisMid longitudinal strainTranscatheter aortic valve implantation

Identifiers

PMID42565928

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.