Evidence map›Paper›PMID 42565922›Full record

ArticleClinical journal of gastroenterology2026

Multifocal primary hepatic epithelioid hemangioendothelioma: a case in which tumor biopsy was critical to prevent misdiagnosis.

Yuya Matsuo, Keisuke Nakanishi, Shinsaku Nagamatsu, Akane Kawasaki, Takuma Morimoto, Satoshi Watanabe, Takahiro Kubo, Masakazu Uejima, Kohei Morita, Kei Moriya

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In one paragraph

Article in Clinical journal of gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

10 authors.

Yuya MatsuoDepartment of Gastroenterology and Hepatology, Nara Prefecture General Medical Center, 2-897-5, Shichijo-Nishimachi, Nara, 630-8581, Japan.
Keisuke NakanishiDepartment of Gastroenterology and Hepatology, Nara Prefecture General Medical Center, 2-897-5, Shichijo-Nishimachi, Nara, 630-8581, Japan.
Shinsaku NagamatsuDepartment of Gastroenterology and Hepatology, Nara Prefecture General Medical Center, 2-897-5, Shichijo-Nishimachi, Nara, 630-8581, Japan.
Akane KawasakiDepartment of Gastroenterology and Hepatology, Nara Prefecture General Medical Center, 2-897-5, Shichijo-Nishimachi, Nara, 630-8581, Japan.
Takuma MorimotoDepartment of Gastroenterology and Hepatology, Nara Prefecture General Medical Center, 2-897-5, Shichijo-Nishimachi, Nara, 630-8581, Japan.
Satoshi WatanabeDepartment of Gastroenterology and Hepatology, Nara Prefecture General Medical Center, 2-897-5, Shichijo-Nishimachi, Nara, 630-8581, Japan.
Takahiro KuboDepartment of Gastroenterology and Hepatology, Nara Prefecture General Medical Center, 2-897-5, Shichijo-Nishimachi, Nara, 630-8581, Japan.
Masakazu UejimaDepartment of Gastroenterology and Hepatology, Nara Prefecture General Medical Center, 2-897-5, Shichijo-Nishimachi, Nara, 630-8581, Japan.
Kohei MoritaDepartment of Pathology, Nara Prefecture General Medical Center, Nara, Japan.
Kei MoriyaDepartment of Gastroenterology and Hepatology, Nara Prefecture General Medical Center, 2-897-5, Shichijo-Nishimachi, Nara, 630-8581, Japan. moriyak@naramed-u.ac.jp.ORCID http://orcid.org/0000-0002-7500-6728

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatic epithelioid hemangioendothelioma is rare, and because its imaging findings are nonspecific, pathological evaluation is essential for definitive diagnosis. In this 82‑year‑old woman, multiple hepatic masses were incidentally detected on contrast‑enhanced CT during postoperative surveillance for bladder cancer, and concurrent local recurrence made metastasis the leading suspicion. However, immunohistopathological examination of a liver biopsy excluded metastatic carcinoma and confirmed primary hepatic epithelioid hemangioendothelioma. She died of liver failure. This case underscores the need to consider diagnoses other than metastatic liver cancer and to perform an appropriate differential workup, even in patients with multiple hepatic lesions and a history of malignancy.

Indexed as

Hemangioendothelioma, EpithelioidLiver NeoplasmsAged, 80 and overBiopsyDiagnosis, DifferentialDiagnostic ErrorsFatal OutcomeFemaleHumansLiverTomography, X-Ray ComputedDifferential diagnosisEpithelioid hemangioendotheliomaHistological examinationLiver biopsyMetastatic liver tumor

Identifiers

PMID42565922

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.