Evidence map›Paper›PMID 42565834›Full record

ArticleSkeletal radiology2026

Diagnostic performance of zero-echo time (ZTE) MRI for preoperative evaluation of cervical OPLL complicated with dural ossification (DO): a retrospective study.

Baiyang Jiang, Qianxi Jin, Dongqing Zhu, Xin Zhang, Weijin Zhang, Jiayi Zhang, Guangwen Duan, Meiling Xu, Xuegao Wu, Wenwen Wang and 6 more

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Article in Skeletal radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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16 authors.

Baiyang Jiang *Department of Radiology, Second Affiliated Hospital of Naval Medical University, Shanghai, 200003, China.
Qianxi Jin *Department of Radiology, Second Affiliated Hospital of Naval Medical University, Shanghai, 200003, China.
Dongqing Zhu *Department of Radiology, Second Affiliated Hospital of Naval Medical University, Shanghai, 200003, China.
Xin ZhangDepartment of Radiology, Second Affiliated Hospital of Naval Medical University, Shanghai, 200003, China.
Weijin ZhangDepartment of Orthopedic Surgery, Second Affiliated Hospital of Naval Medical University, Shanghai, 200003, China.
Jiayi ZhangDepartment of Radiology, Second Affiliated Hospital of Naval Medical University, Shanghai, 200003, China.
Guangwen DuanDepartment of Radiology, Second Affiliated Hospital of Naval Medical University, Shanghai, 200003, China.
Meiling XuDepartment of Radiology, Second Affiliated Hospital of Naval Medical University, Shanghai, 200003, China.
Xuegao WuDepartment of Radiology, Second Affiliated Hospital of Naval Medical University, Shanghai, 200003, China.
Wenwen WangDepartment of Radiology, Second Affiliated Hospital of Naval Medical University, Shanghai, 200003, China.
Song JiangDepartment of Radiology, Second Affiliated Hospital of Naval Medical University, Shanghai, 200003, China.
Fukai LiDepartment of Radiology, Second Affiliated Hospital of Naval Medical University, Shanghai, 200003, China.
Xiang WangDepartment of Radiology, Second Affiliated Hospital of Naval Medical University, Shanghai, 200003, China.
Tiefeng LiDepartment of Orthopedic Surgery, Second Affiliated Hospital of Naval Medical University, Shanghai, 200003, China. litiefeng008@163.com.
Yi XiaoDepartment of Radiology, Second Affiliated Hospital of Naval Medical University, Shanghai, 200003, China. czyyxiaoyi@163.com.
Shiyuan LiuDepartment of Radiology, Second Affiliated Hospital of Naval Medical University, Shanghai, 200003, China. radiology_cz@163.com.

Funding

Shanghai Leading Talent Program of Eastern Talent Plan No. LJ2023094
6 · The paper itself

Abstract

objectiveTo evaluate the diagnostic efficacy of zero-echo time (ZTE) magnetic resonance imaging (MRI) for cervical ossification of the posterior longitudinal ligament (OPLL) complicated by dural ossification (DO), compared with T1-weighted imaging (T1WI) and T2-weighted imaging (T2WI). MATERIALS AND

methodsThis retrospective single-center study included 73 consecutive OPLL patients (52 males, 21 females; mean age 55.5 ± 10.6 years) admitted between April 2025 and October 2025. All underwent 1-mm thin-slice computed tomography (CT) (gold standard) and 3.0T MRI (T1WI, T2WI, and ZTE). Two senior radiologists blindly assessed DO presence. Sensitivity, specificity, diagnostic accuracy, area under the curve (AUC), and Cohen's κ interobserver agreement coefficient were calculated, with McNemar's and DeLong's tests applied for interreader and pairwise AUC statistical comparisons, respectively.

resultsCT confirmed 46 cases (63.0%) of cervical OPLL complicated with DO. For the ZTE sequence, the diagnostic sensitivity of the two readers was 93.5% and 95.7%, specificity was 96.3% and 88.9%, accuracy was 94.5% and 93.2%, and AUC was 0.949 and 0.923, respectively. These metrics were significantly superior to those of T1WI imaging (AUC 0.522-0.536) and T2WI imaging (AUC 0.550-0.572). DeLong's test confirmed that the AUC of ZTE was significantly higher than that of T1WI (P < 0.001) and T2WI (p < 0.001), while there was no significant difference between T1WI and T2WI (p > 0.05). Regarding interobserver consistency: the Cohen's κ value for ZTE was 0.854, while those for T1WI and T2WI were -0.043 and 0.466, respectively.

conclusionZTE-MR imaging offers a nonionizing, highly sensitive, and reproducible approach for diagnosing cervical OPLL with DO and serves as a valuable adjunct to conventional sequences for preoperative evaluation.

Indexed as

Cervical VertebraeDura MaterMagnetic Resonance ImagingOssification of Posterior Longitudinal LigamentAgedFemaleHumansMaleMiddle AgedPreoperative CareReproducibility of ResultsRetrospective StudiesSensitivity and SpecificityTomography, X-Ray ComputedCervical ossification of the posterior longitudinal ligamentDiagnostic performanceDural ossificationRetrospective studyZero-echo time MRI

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.