ArticleEuropean journal of applied physiology2026
The relationship between post-occlusive reactive hyperemia and the level of training and lifestyle in young adults.
Article in European journal of applied physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundPost-occlusive reactive hyperemia (PORH) is widely used to assess microvascular function. Increasing attention has been directed toward temporal characteristics of the PORH response and the need for individualized arterial occlusion pressure (AOP); however, comparative data across athletes with different training profiles and non-athletic controls remain limited. PURPOSE: To compare PORH-derived microcirculatory parameters among individuals with different training backgrounds using an individualized AOP approach.
methodsThis cross-sectional study included 60 participants (n = 60, 50 males and 10 females) divided into four groups (n = 15 each): marathon runners, bodybuilders, mixed martial arts (MMA) athletes, and non-athletic controls. PORH was assessed using laser Doppler flowmetry (LDF). The analyzed parameters included resting flow (RF), biological zero (BZ), maximum peak perfusion (MAX Peak), time to peak perfusion (TP), and time to recovery (TTR). Between-group comparisons were performed using the Kruskal-Wallis test with post-hoc analysis, and effect size was calculated (ε
resultsThe Kruskal-Wallis test revealed a significant between-group difference only for TP (H = 18.914; p = 0.0003; ε
conclusionsTime to peak perfusion is a sensitive parameter distinguishing microvascular responses across training profiles. A shorter time to peak perfusion (TP) is generally interpreted as a more efficient microvascular response and improved vascular reactivity. MMA athletes demonstrate a faster microvascular response following occlusion, likely reflecting training-specific vascular adaptations associated with mixed, high-intensity exercise. These findings highlight the importance of AOP individualization and the use of temporal PORH parameters in microcirculatory assessment of athletes.
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