ArticleZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences2026
[Factors influencing pregnancy decision-making among parents of fetuses with congenital heart disease].
Article in Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesIn the context of prenatal counseling, the factors influencing pregnancy decision-making among parents of fetuses with congenital heart disease (CHD) remain unclear. This study aims to investigate the factors influencing pregnancy decision-making among parents of fetuses with CHD, with a particular focus on the roles of non-medical factors such as psychological status, socioeconomic status, and the degree of fetal expectation.
methodsA prospective cohort study design was adopted. Expectant parents whose fetuses were prenatally diagnosed with CHD at the Second Xiangya Hospital of Central South University and Hunan Provincial Maternal and Child Health Care Hospital from July 2021 to December 2025, and who received multidisciplinary counseling led by CHD specialists, were enrolled. According to the prognostic risk scoring system, the fetuses were classified into a mild group (0-3 points), a moderate group (4-6 points), and a severe group (7-9 points).Information on the fetuses and parents was collected through questionnaires, and follow-up files were established. Standardized follow-up was conducted at 1 week after counseling, 1 to 2 weeks before the expected date of delivery, and 2 weeks after the expected date of delivery to record the pregnancy outcomes. Multivariate Logistic regression analysis was used to identify independent factors influencing pregnancy decision-making.
resultsA total of 834 families with fetuses prenatally diagnosed with CHD were included. Among them, 522 families (62.6%) chose to continue the pregnancy, whereas 312 families (37.4%) chose to terminate the pregnancy. The severity of fetal disease was the strongest predictor of pregnancy termination. Compared with the mild group, the risk of pregnancy termination in the moderate group increased by 6-fold [adjusted odds ratio (a
conclusionsPregnancy decision-making among parents of fetuses with CHD is a complex process jointly influenced by fetal medical factors, family socioeconomic status, and psychosocial factors. In addition to disease severity, family economic status, and par ental expectations regarding the fetus have important effects on decision-making.
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