Evidence map›Paper›PMID 42564767›Full record

ArticleFrontiers in neurology

Peripheral/central neural microstructural alterations in persistent idiopathic dentoalveolar pain: a case-comparative study.

Motoko Watanabe, Keigo Shimoji, Junichiro Sakamoto, Chizuko Maeda, Kiyokazu Iwawaki, Gayatri Nayanar, Qinyi Chen, Chihiro Takao, Risa Tominaga, Yasuyuki Kimura and 5 more

Abstract read
PubMed Full text at PMC Publisher
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Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Motoko WatanabeDepartment of Psychosomatic Dentistry, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.
Keigo ShimojiDepartment of Radiology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Junichiro SakamotoDepartment of Dental Radiology and Radiation Oncology, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.
Chizuko MaedaDepartment of Psychosomatic Dentistry, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.
Kiyokazu IwawakiDepartment of Psychosomatic Dentistry, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.
Gayatri NayanarDepartment of Psychosomatic Dentistry, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.
Qinyi ChenDepartment of Psychosomatic Dentistry, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.
Chihiro TakaoDepartment of Psychosomatic Dentistry, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.
Risa TominagaDepartment of Psychosomatic Dentistry, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.
Yasuyuki KimuraDepartment of Psychosomatic Dentistry, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.
Atsushi ItoDepartment of Psychosomatic Dentistry, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.
Trang Hu Thi TuDepartment of Psychosomatic Dentistry, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.
Masahiko MiuraDepartment of Dental Radiology and Radiation Oncology, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.
Akihiko WadaDepartment of Radiology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Akira ToyofukuDepartment of Psychosomatic Dentistry, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Persistent idiopathic dentoalveolar pain (PIDAP) has been considered to involve the predominant peripheral or central nervous system, but details of mechanisms remain unclear. This study investigated differences in clinical characteristics and microstructural integrity at the peripheral trigeminal nerve and central white matter between patients with PIDAP, depending on the presence or absence of neurovascular compression (NVC) at the root entry zone (REZ). This retrospective case-comparative study enrolled patients with PIDAP who underwent diffusion tensor imaging to evaluate neural integrity by fractional anisotropy (FA). FA of the trigeminal nerve at the REZ was assessed as a peripheral interaction, and FA in the white matter was assessed as a central interaction. Among 27 patients with NVC and 39 without NVC, pain intensity was significantly higher in patients without NVC (44.3 ± 27.5; 58.6 ± 25.4;

Indexed as

atypical odontalgiacentral sensitizationdiffusion tensor imagemagnetic resonance imageneurovascular compressionpain catastrophizingpersistent idiopathic dentoalveolar painsomatic symptom burden

Identifiers

PMID42564767
PMCPMC13445719

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.