Evidence map›Paper›PMID 42564756›Full record

ArticleRadiology case reports2026

A rare case of lacrimal gland adenocarcinoma successfully treated with carbon ion radiotherapy.

Caterina Benedetto, Ugo Barbaro, Carmelo Anfuso, Fabio Italiano, Danilo Caudo, Fabiana Giacò, Giuseppe Cicero

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Radiology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Caterina BenedettoDepartement of Radiology, I.R.C.C.S. Centro Neurolesi Bonino Pulejo, Messina, Italy.
Ugo BarbaroDepartement of Radiology, I.R.C.C.S. Centro Neurolesi Bonino Pulejo, Messina, Italy.
Carmelo AnfusoDepartement of Radiology, I.R.C.C.S. Centro Neurolesi Bonino Pulejo, Messina, Italy.
Fabio ItalianoDepartement of Radiology, I.R.C.C.S. Centro Neurolesi Bonino Pulejo, Messina, Italy.
Danilo CaudoDepartement of Radiology, I.R.C.C.S. Centro Neurolesi Bonino Pulejo, Messina, Italy.
Fabiana GiacòDepartement of Radiology, I.R.C.C.S. Centro Neurolesi Bonino Pulejo, Messina, Italy.
Giuseppe CiceroDepartement of Radiology, I.R.C.C.S. Centro Neurolesi Bonino Pulejo, Messina, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary malignant tumors of the lacrimal gland are very rare. The standard treatment typically involves wide surgical excision, which may include orbital bone resection and enucleation of the eyeball, followed by adjuvant radiotherapy. Recent advancements in hadron therapy, particularly carbon-ion radiotherapy, enable highly precise dose delivery to the tumor while minimizing exposure to surrounding healthy tissues, which could reduce toxicity. We report the case of a 70-year-old man diagnosed with asymptomatic primary ductal adenocarcinoma of the lacrimal gland. After a conservative microsurgical excision, residual disease remained, prompting the patient to undergo carbon-ion radiotherapy, which resulted in complete resolution of the tumor with minimal toxicity.

Indexed as

Carbon-ion radiotherapy (CIRT)HadrontherapyLacrimal gland neoplasmOrbital tumor managementOrgan-preserving therapyPrimary ductal adenocarcinoma of the lacrimal gland (PDACL)

Identifiers

PMID42564756
PMCPMC13446182

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.