Evidence map›Paper›PMID 42564733›Full record

ArticleEnvironmental health perspectives2026

In Utero Per- and Polyfluoroalkyl Substances (PFAS) Exposure and Changes in Infant T Helper Cell Development among UPSIDE-ECHO Cohort Participants.

Darline Castro-Melendez, Nathan Laniewski, Todd Jusko, Xing Qiu, B Paige Lawrence, Zorimar Rivera-Núñez, Brunner Jessica, Meghan Best, Allison Macomber, Alena Leger and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environmental health perspectives, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Developmental exposure to a PFAS mixture impairs the anamnestic response to influenza A virus infection in mice.Toxicological sciences : an official journal of the Society of Toxicology · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Darline Castro-MelendezDepartment of Immunology, Microbiology and Virology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, United States.ORCID https://orcid.org/0000-0001-9743-833X
Nathan LaniewskiDepartment of Pediatrics, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, United States.
Todd JuskoDepartment of Public Health Sciences, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, United States.
Xing QiuDepartments of Biostatistics and Computational Biology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, United States.
B Paige LawrenceDepartment of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, United States.
Zorimar Rivera-NúñezDepartment of Biostatistics and Epidemiology, Rutgers School of Public Health, Environmental and Occupational Health Sciences Institute, Piscataway, New Jersey 08854, United States.ORCID https://orcid.org/0000-0002-0718-1807
Brunner JessicaDepartment of Obstetrics and Gynecology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, United States.
Meghan BestDepartment of Obstetrics and Gynecology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, United States.
Allison MacomberDepartment of Obstetrics and Gynecology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, United States.
Alena LegerDepartment of Obstetrics and Gynecology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, United States.
Kurunthachalam KannanDepartment of Environmental Health Sciences, College of Integrated Health Sciences, University at Albany, Albany, New York 12222, United States.ORCID https://orcid.org/0000-0002-1926-7456
Richard K MillerDepartment of Obstetrics and Gynecology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, United States.
Emily S BarretDepartment of Biostatistics and Epidemiology, Rutgers School of Public Health, Environmental and Occupational Health Sciences Institute, Piscataway, New Jersey 08854, United States.
Thomas G O'ConnorDepartments of Psychiatry, Neuroscience, Obstetrics and Gynecology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, United States.
Kristin ScheibleDepartment of Pediatrics, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, United States.

Funding

VISUAL INDICES OF NEUROTOXICITYP30ES001247 · NIEHS · UNIVERSITY OF ROCHESTER · PI Martha Susiarjo · 1985 to 2026
$42.8M
The University of Rochester's Clinical and Translational Science InstituteUL1TR002001 · NCATS · UNIVERSITY OF ROCHESTER · PI WILSON, KAREN M., ZAND, MARTIN S · 2016 to 2024
$34.6M
Pre- and Postnatal Exposure Periods for Child Health: Common Risks and Shared MechanismsUH3OD023349 · OD · UNIVERSITY OF ROCHESTER · PI Emily S Barrett, Richard Kermit Miller · 2018 to 2026
$15.9M
The T32 Predoctoral Training Program in Immunology (PTPI)T32AI007285 · NIAID · UNIVERSITY OF ROCHESTER · PI Scott Andrew Gerber, JACQUES Robert · 1986 to 2026
$7.6M
Understanding Prenatal Signals and Infant Development (UPSIDE)R01HD083369 · NICHD · UNIVERSITY OF ROCHESTER · PI BARRETT, EMILY S · 2015 to 2019
$2.6M
Developmental immunotoxicity of PFASR01ES036197 · NIEHS · UNIVERSITY OF ROCHESTER · PI B Paige Lawrence · 2024 to 2026
$1.4M
NCATS NIH HHS UL1 TR002001NIAID NIH HHS T32 AI007285NICHD NIH HHS R01 HD083369NIEHS NIH HHS P30 ES001247NIEHS NIH HHS R01 ES036197NIH HHS UH3 OD023349
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Environmental PollutantsFluorocarbonsMaternal ExposurePrenatal Exposure Delayed EffectsT-Lymphocytes, Helper-InducerAdultCohort StudiesFemaleHumansInfantInfant, NewbornMalePregnancyEnvironmental PollutantsFluorocarbons

Identifiers

PMID42564733
PMCPMC13445270

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.