Evidence map›Paper›PMID 42564708›Full record

ArticleAfrican health sciences2026

Prediabetes and diabetes among patients presenting with acute stroke or acute coronary syndrome at a tertiary regional referral centre in Kenya.

Beverly Owino, Jasmit Shah, Hasina Visram, Eric Njenga, Nancy Kunyiha

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Article in African health sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Beverly OwinoDepartment of Internal Medicine, Aga Khan University, Nairobi, Kenya.
Jasmit ShahDepartment of Internal Medicine, Aga Khan University, Nairobi, Kenya.
Hasina VisramEndocrinology and Metabolism, West Ottawa Specialty care, Ontario, Canada.
Eric NjengaDepartment of Internal Medicine, Aga Khan University, Nairobi, Kenya.
Nancy KunyihaDepartment of Internal Medicine, Aga Khan University, Nairobi, Kenya.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Diabetes and pre-diabetes are significant risk factors for acute coronary syndrome (ACS) and acute primary stroke (APS). Dysglycemia in any context is under-diagnosed or identified late in resource-poor countries such as in sub-Saharan Africa (SSA), especially when the patient is not known to have pre-morbid diabetes. Materials and methods: We conducted a prospective cross-sectional study at the Aga Khan University Hospital, Nairobi. Inclusion criteria: consenting adults ≥18 years admitted with ACS/APS during the period April 2021-February 2022 inclusive. HbA1C was used to determine the glycemic status. Definition of diabetes and pre-diabetes was based on the American Diabetes Association guidelines. Results: From a total of 211 patients [144 (81.2%) of African race], the median age of the patients was 58 (49-68) years with a male to female ratio of 2.5:1. 47.4% (n = 100) had ACS and 52.6% (n=111) had APS. The prevalence of dysglycemia was 68.2% (95% CI: 61.5%-74.5%) with the prevalence of pre-diabetes being 30.3% (64/211) and type 2 diabetes 37.9% (80/211). Of the patients with dysglycemia, 47.9% (69/144) had a new diagnosis. Conclusion: This study shows a remarkably high prevalence of dysglycemia in patients with ACS/APS. The new diagnosis of pre-diabetes prevalence was comparable to diabetes in these patients, adding to the evidence that prediabetes portends significant cardiometabolic consequences and effects over and above the development of type 2 diabetes.

Indexed as

Acute Coronary SyndromeDiabetes Mellitus, Type 2Prediabetic StateStrokeAgedBlood GlucoseCross-Sectional StudiesFemaleGlycated HemoglobinHumansKenyaMaleMiddle AgedPrevalenceProspective StudiesRisk FactorsBlood GlucoseGlycated HemoglobinAcute Coronary SyndromeDiabetesMacrovascularPrediabetesStroke

Identifiers

PMID42564708
PMCPMC13444293

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.