ArticleEnvironmental health perspectives2026
A New Mouse Model for Ozone Health Effects Research.
Article in Environmental health perspectives, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
7 authors.
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Abstract
backgroundExposure to the ambient air pollutant ozone (O
objectivesFirst, to test whether a recombinant inbred mouse strain from the Collaborative Cross population, CC002/Unc, provides a sensitive model of ozone response by benchmarking it to the most commonly used inbred strain, C57BL/6J. Second, to identify the genetic basis of CC002/Unc's sensitivity.
methodsWe examined the responses of CC002/Unc and C57BL/6J mice to either acute (0.4 or 0.8 ppm O
resultsCC002/Unc was far more responsive to acute O DISCUSSION: The CC002/Unc strain provides an improved model to study the effects of acute and repeated O
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.