Evidence map›Paper›PMID 42564653›Full record

ArticleAnimal welfare (South Mimms, England)2026

A solution right under our nose? Crossbreeding extreme brachycephalic dogs results in better health outcomes while preserving behavioural profiles and dog-owner relationship quality.

Elizabeth Youens, Dan G O'Neill, Mickey Tivers, Zoe Belshaw, Johanna Neufuss, Rowena M A Packer

Abstract read
In one paragraph

Article in Animal welfare (South Mimms, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elizabeth YouensClinical Science and Services, Royal Veterinary College, Herts, UK.
Dan G O'NeillPathobiology and Population Sciences, Royal Veterinary College, Herts, UK.
Mickey TiversParagon Veterinary Referrals, Wakefield, UK.
Zoe BelshawEviVet Evidence-Based Veterinary Consultancy, Nottingham, UK.
Johanna NeufussBlue Cross, Burford, UK.
Rowena M A PackerClinical Science and Services, Royal Veterinary College, Herts, UK.ORCID https://orcid.org/0000-0002-9988-9828

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite substantial evidence of numerous welfare-limiting disorder predispositions linked to their exaggerated conformation, brachycephalic dogs remain highly desired breeds in the UK. National and international attempts to reduce demand for brachycephalic breeds appear to have had a limited effect on significantly reducing their acquisition. As 'designer crossbreeds' become increasingly popular, an opportunity exists to leverage the public's desire for intentionally crossbred dogs to meet the ownership niche currently occupied by extreme brachycephalic dogs. However, evidence on the comparative health, behaviour and dog-owner relationship between extreme brachycephalic purebreds and their less extreme designer crosses is urgently needed to understand whether they are truly higher-welfare. Purebred Pug (n = 51) and Pug-cross ('Jug': Jack Russell × Pug; n = 51; and 'Puggle': Beagle × Pug; n = 48) dogs were recruited from the UK pet-owned population for veterinary health assessments and to assess owner-reported health, behaviour and dog-owner relationships using established tools. Jugs and Puggles had a less extreme facial conformation than Pugs, with significantly longer relative muzzle length and less stenotic nostrils. Purebred Pugs exhibited a significantly higher prevalence of respiratory, ocular, dermatological and musculoskeletal disorders compared to Jugs and Puggles, and accrued increased veterinary costs. However, behaviour profiles and dog-owner relationships were similar between purebred and designer crossbred dogs. These results provide strong evidence of substantially reduced conformation-related disorder burden in designer crossbreed Pugs compared to their purebred Pug progenitor, whilst preserving behaviour profiles and dog-owner relationships that are known key motivators for extreme brachycephalic acquisition. Crossbreeding offers major opportunities to improve the welfare of extreme brachycephalic dogs.

Indexed as

Animal welfarebreedingcanineconformationcrossbreedoutcross

Identifiers

PMID42564653
PMCPMC13443976

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.