Evidence map›Paper›PMID 42564590›Full record

ArticleRadiology case reports2026

Lumbosacral aggressive osteoblastoma with extensive flare phenomenon: A diagnostic pitfall.

Demamu Agegn, Hilaludin Mohammed, Kifle Tadesse, Helen Tesfay Tadesse, Zewditu Nigatu, Bethelhem Belachew, Biniyam Beyene Tabor

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PubMed Full text at PMC Publisher
In one paragraph

Article in Radiology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Demamu AgegnDepartment of Radiology, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Hilaludin MohammedDepartment of Radiology, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Kifle TadesseDepartment of Radiology, Addis Ababa University, College of Health Sciences, Addis Ababa, Ethiopia.
Helen Tesfay TadesseDepartment of Pathology, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Zewditu NigatuDepartment of Pathology, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Bethelhem BelachewDepartment of Radiology, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Biniyam Beyene TaborDepartment of Radiology, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While osteoblastoma is a rare benign bone-forming tumor, its aggressive variant can mimic malignant bone tumors. This resemblance is especially pronounced when accompanied by a flare phenomenon. We report a 12-year-old female with progressive neurological deficits and a lumbosacral mass. The initial MRI suggested a malignant bone tumor due to an ill-defined, avidly enhancing lesion at L4-S1 with severe canal stenosis. However, CT imaging revealed a more benign appearance, showing a well-defined lytic-sclerotic lesion with a narrow zone of transition. Histopathology confirmed the diagnosis of an aggressive osteoblastoma. This case highlights the importance of recognizing the flare phenomenon as a potential imaging pitfall in aggressive osteoblastoma, emphasizing the necessity of multimodal imaging-histopathology correlation for correct diagnosis and management.

Indexed as

Aggressive osteoblastomaDiagnostic pitfallFlare phenomenonLumbosacral spine

Identifiers

PMID42564590
PMCPMC13444488

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