Evidence map›Paper›PMID 42564478›Full record

ReviewHealth science reports2026

Efficacy and Safety of Ultrasound-Guided Nerve Block Versus Local Anesthesia for Arteriovenous Fistula Angioplasty: A Systematic Review and Meta-Analysis.

Wenshen Pu, Zhihu Chen, Zhangjian Xu, Yi Zhang, Zhidao Wang, Bingjie Wang, Ziming Wan

Abstract readReview
In one paragraph

Review in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wenshen PuDepartment of Nephrology Baoshan People's Hospital Baoshan China.ORCID https://orcid.org/0000-0002-8232-6455
Zhihu ChenDepartment of Nephrology Chuxiong Yi Autonomous Prefecture People's Hospital Chuxiong China.
Zhangjian XuDepartment of Nephrology Baoshan People's Hospital Baoshan China.
Yi ZhangDepartment of Nephrology Baoshan People's Hospital Baoshan China.
Zhidao WangDepartment of Nephrology Chuxiong Yi Autonomous Prefecture People's Hospital Chuxiong China.
Bingjie WangDepartment of Nephrology Baoshan People's Hospital Baoshan China.
Ziming WanDepartment of Nephrology The First Affiliated Hospital of Chongqing Medical University Chongqing China.ORCID https://orcid.org/0000-0001-6699-654X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Severe intra-procedural pain commonly complicates percutaneous transluminal angioplasty (PTA) for dysfunctional arteriovenous fistulas (AVFs), undermining patient cooperation and potentially increasing the need for sedative medications. This systematic review and meta-analysis aimed to evaluate the analgesic efficacy, safety, and clinical performance of ultrasound-guided nerve block (UGNB) versus local anesthesia (LA) in adult patients undergoing AVF PTA. Methods: We searched PubMed, Embase, Scopus, the Cochrane Library, and Web of Science for eligible randomized controlled trials and cohort studies published up to September 1, 2025. The primary outcome was intra-procedural pain rated using VAS or NRS on a 0-10 scale. The secondary outcome was overall safety, assessed using the available complication-free outcome. Random-effects models were used for pooled analyses. Heterogeneity was explored using Galbraith plots and leave-one-out analyses. Funnel plots were generated for exploratory visualization because fewer than 10 studies were included. Subgroup analyses were performed according to UGNB subtype, and an exploratory subgroup analysis was additionally conducted by study design. Results: Four eligible studies, including 664 participants from East Asia, were included in the quantitative synthesis. In the primary pain analysis, UGNB was associated with a marked reduction in intra-procedural pain relative to LA (SMD -2.85, 95% CI -4.70 to -1.01; Conclusion: UGNB was associated with superior analgesia without a clear increase in adverse events during AVF PTA. Current evidence does not establish a statistically significant difference between BPB and SCNB, and the SCNB subgroup should be interpreted cautiously because of substantial heterogeneity. Larger multicenter trials are needed to compare block techniques directly and to evaluate recovery, patency, and cost-effectiveness.

Indexed as

arteriovenous fistulaslocal anesthesiameta‐analysispercutaneous transluminal angioplastyultrasound‐guided nerve blocks

Identifiers

PMID42564478
PMCPMC13443139

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.