Evidence map›Paper›PMID 42564473›Full record

ArticleSage open pediatrics

Incidence of Neonatal Meningitis and the Premature Mortality in Eastern Sub-saharan Africa, From 1990 to 2023: A Global Burden of Diseases Study.

Sebsibe Tadesse, Tibeso Gemechu, Kebebew Lemma, Embay Amare Alemseged, Abraham Lomboro Dimore, Hiwot Hailu Amare, Jemal Bedewi, Zufan Tessema, Abera Mersha, Yemane Berhane Tesfau and 8 more

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Article in Sage open pediatrics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Sebsibe TadesseSchool of Public Health, Institute of Health, Bule Hora University, Bule Hora, Oromia, Ethiopia.
Tibeso GemechuDepartment of Medical Laboratory Science, Institute of Health, Bule Hora University, Bule Hora, Ethiopia.
Kebebew LemmaSchool of Public Health, Institute of Health, Bule Hora University, Bule Hora, Oromia, Ethiopia.
Embay Amare AlemsegedDepartment of Public Health, College of Medicine and Health Sciences, Adigrat University, Adigrat, Ethiopia.
Abraham Lomboro DimoreDepartment of Epidemiology and Biostatistics, Faculty of Public Health, Institute of Health Science, Jimma University, Ethiopia.
Hiwot Hailu AmareSchool of Public Health, College of Medicine and Health Sciences, Dilla University, Dilla, Ethiopia.ORCID https://orcid.org/0000-0001-9116-274X
Jemal BedewiDepartment of Public Health, College of Medicine and Health Sciences, Wolkite University, Wolkite, Ethiopia.
Zufan TessemaCollege of Medicine and Health Science, Wolkite University, Wolkite, Ethiopia.
Abera MershaDepartment of Comprehensive Nursing, Nursing and Midwifery Education and Service Director, Arba Minch University, Arba Minch, Ethiopia.ORCID https://orcid.org/0000-0002-4366-4128
Yemane Berhane TesfauSchool of Public Health, College of Medicine and Health Sciences, Adigrat University, Adigrat, Ethiopia.ORCID https://orcid.org/0000-0002-9146-5940
Embaba Tekelaye WelesemayatDepartment of Epidemiology and Biostatistics, School of Public Health, College of Health Science, Aksum University, Aksum, Ethiopia.ORCID https://orcid.org/0000-0003-1591-1600
Boko Loka SafayiDepartment of Pediatrics and Child Health Nursing, Institute of Health, Bule Hora University, Bule Hora, Ethiopia.ORCID https://orcid.org/0000-0002-3160-4347
Alqeer AliyoDepartment of Medical Laboratory Science, Institute of Health, Bule Hora University, Bule Hora, Ethiopia.ORCID https://orcid.org/0000-0001-7301-5332
Belda Negesa BeyeneDepartment of Midwifery, Institute of Health, Bule Hora University, Bule Hora, Oromia, Ethiopia.
Girma AshenafiDepartment of Medical Laboratory Science, Institute of Health, Bule Hora University, Bule Hora, Ethiopia.
Geleta Nenko DubeSchool of Public Health, Institute of Health, Bule Hora University, Bule Hora, Oromia, Ethiopia.ORCID https://orcid.org/0009-0003-1919-874X
Beka Yambo JofaSchool of Public Health, Institute of Health, Bule Hora University, Bule Hora, Oromia, Ethiopia.ORCID https://orcid.org/0009-0005-8348-6636
Anteneh FikrieSchool of Public Health, Institute of Health, Bule Hora University, Bule Hora, Oromia, Ethiopia.ORCID https://orcid.org/0000-0002-9809-3326

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Quantify neonatal meningitis incidence and years of life lost (YLLs) in Eastern Sub-Saharan Africa (ESSA) from 1990 to 2023. Methods: Secondary analysis of GBD data analyzed temporal trends by location, year and sex. Bayesian meta-regression estimated incidence, cause of death ensemble modeling calculated YLLs, and spatiotemporal Gaussian process regression smoothed trends. Estimates include 95% uncertainty intervals (UIs). Results: In 2023, ESSA's neonatal meningitis incidence rate was 2,542 per 100,000 (95% UI: 2,043-3,065), heavily concentrated in early neonates (5,415) versus late neonates (1,574). The regional YLL rate was 24,855 per 100,000, driven by early neonates (66,882). Somalia and South Sudan exceeded regional averages. Globally, YLL rates declined from 1990 to 2023 (Annual Rate of Change: -0.70%). Conclusion: ESSA faces a severe neonatal meningitis burden skewed toward early neonates. Urgent strategies must scale up maternal screening, intrapartum antibiotics, and rapid diagnostics for fast-tracked treatment.

Indexed as

early neonateESSAGBDlate neonateneonatal meningitispremature mortalityYLLs

Identifiers

PMID42564473
PMCPMC13443256

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.