Evidence map›Paper›PMID 42564459›Full record

SynthesisFrontiers in pain research (Lausanne, Switzerland)2026

Hydrodissection and hydrodilatation for joint pain: a scoping review.

Benjamin Leahy, Harry McGrath, Dominic Harmon

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in pain research (Lausanne, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Benjamin LeahyDepartment of Anaesthesia and Pain Medicine, University Hospital Limerick, Limerick, Ireland.
Harry McGrathDepartment of Anaesthesia and Pain Medicine, University Hospital Limerick, Limerick, Ireland.
Dominic HarmonDepartment of Anaesthesia and Pain Medicine, University Hospital Limerick, Limerick, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate the current evidence regarding the effectiveness and safety of ultrasound-guided hydrodissection (US-HD) in the management of joint-related pain. Methods: A systematic search of PubMed, Embase, Cochrane Library, and Google Scholar was conducted for studies published in the past 15 years. Eligible studies included randomised controlled trials (RCTs), cohort studies, and case series investigating hydrodissection for joint pain (e.g., shoulder, hip, knee, sacroiliac joint). Outcomes included pain reduction, functional improvement, and complication rates. Data extraction and qualitative synthesis were performed due to heterogeneity in study design and outcome measures. Results: A total of 138 studies were identified, of which 21 met inclusion criteria. Evidence suggests that US-HD may provide significant pain relief and functional improvement in conditions such as adhesive capsulitis, greater trochanteric pain syndrome, and knee osteoarthritis. Studies consistently reported low complication rates. However, heterogeneity in technique, injectate composition, and outcome measures was noted. Conclusion: Ultrasound-guided hydrodissection appears to be a safe and promising intervention for joint-related pain. While early evidence is encouraging, larger high-quality trials are required to establish standardised protocols and confirm long-term efficacy.

Indexed as

adhesive capsulitishydrodissectionjoint painmusculoskeletal painsystematic reviewultrasound-guided injection

Identifiers

PMID42564459
PMCPMC13443037

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.