Evidence map›Paper›PMID 42564410›Full record

ReviewHepatology forum2026

Occult hepatitis B infection.

Mikha Eliana Wati, Yusra

Abstract readReview
In one paragraph

Review in Hepatology forum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mikha Eliana WatiDepartment of Clinical Pathology, Universitas Indonesia, Jakarta, Indonesia.
YusraDepartment of Clinical Pathology, Universitas Indonesia, Jakarta, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Occult Hepatitis B Infection (OBI) is a condition in which HBsAg tests are negative, but Hepatitis B virus (HBV) DNA is detectable in the liver, with or without low levels of HBV DNA in the blood (<200 IU/mL). The Hepatitis B surface antigen (HBsAg) negative status in OBI may result from the absence or low production of HBsAg due to immune system defense mechanisms or mutations in the S genome of HBV DNA, which make HBsAg undetectable. The gold standard for diagnosing OBI is testing for HBV DNA from liver tissue, with an alternative method being HBV DNA testing from serum. Patients with OBI may be at risk of transmitting HBV to others through blood transfusions or organ transplants. Reactivation may occur, especially in OBI patients who are immunocompromised or undergoing immunosuppressive therapy. Antiviral prophylaxis may be considered for OBI patients at risk of reactivation. Additionally, OBI patients also carry a risk of developing hepatocellular carcinoma (HCC), similar to those with non-occult hepatitis B infection. Antiviral therapy for OBI is generally not required unless the case represents false OBI due to HBsAg mutation.

Indexed as

Hepatitis B surface antigenhepatitis B virusoccult hepatitis B infection

Identifiers

PMID42564410
PMCPMC13442727

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.