ArticleFrontiers in stroke2026
Clinical characteristics and frequent risk factors in young adult patients with stroke at a tertiary care hospital in Honduras.
Article in Frontiers in stroke, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Stroke has become the third leading cause of death, accounting for 10% of all deaths. The prevalence of intracranial hemorrhage, subarachnoid hemorrhage, and ischemic stroke has increased by 20.5%, 11.5%, and 7.4%, respectively, in the 20-54 age group, making it a worldwide problem for the young adult population. Aim: To describe the clinical characteristics, diagnostic findings, stroke subtypes, and frequent risk factors among young adult patients with stroke treated at a tertiary care hospital in Honduras. Methods: Cross-sectional, non-probability convenience sample study of 70 patients aged 18-55 years. An ethical opinion was obtained (079-2024). The information was supplemented with clinical examinations, laboratory tests, neuroimaging, carotid Doppler, and transcranial Doppler with bubble test. Descriptive statistics were obtained. Results: Young adults accounted for 30.0% of stroke cases evaluated. The mean age was 43.4 ± 9.1 years. The 61.4% were women, 55.7% had a history of hypertension, 31.4% had type 2 diabetes mellitus, and 24.3% had migraines. A total of 21.4% were smokers, and 15.7% of women used oral contraceptives. Ischemic stroke occurred in 71.4% of cases, with a cardioembolic etiology in 21.4%. A patent foramen ovale (PFO) was identified in 5 of 17 cases, corresponding to 29.4% of the tested subgroup and 7.1% of the total sample and mortality was 15.7%. Conclusions: A high proportion of strokes were observed in women, with a predominance of ischemic strokes of cardioembolic etiology. Modifiable factors associated with stroke were identified, which can be controlled, contributing to a decrease in morbidity and mortality from this pathology.
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