Evidence map›Paper›PMID 42564117›Full record

ArticleFrontiers in immunology2026

Effects of immunosuppression on tracheal mucosal responses after infection with

Sathya N Kulappu Arachchige, Anna Kanci Condello, Amir H Noormohammadi, Kelly A Tivendale, Glenn F Browning, Nadeeka K Wawegama

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sathya N Kulappu ArachchigeAsia-Pacific Centre for Animal Health, Melbourne Veterinary School, Faculty of Science, The University of Melbourne, Parkville, VIC, Australia.
Anna Kanci CondelloAsia-Pacific Centre for Animal Health, Melbourne Veterinary School, Faculty of Science, The University of Melbourne, Parkville, VIC, Australia.
Amir H NoormohammadiAsia-Pacific Centre for Animal Health, Melbourne Veterinary School, Faculty of Science, The University of Melbourne, Werribee, VIC, Australia.
Kelly A TivendaleAsia-Pacific Centre for Animal Health, Melbourne Veterinary School, Faculty of Science, The University of Melbourne, Parkville, VIC, Australia.
Glenn F Browning *Asia-Pacific Centre for Animal Health, Melbourne Veterinary School, Faculty of Science, The University of Melbourne, Parkville, VIC, Australia.
Nadeeka K Wawegama *Asia-Pacific Centre for Animal Health, Melbourne Veterinary School, Faculty of Science, The University of Melbourne, Parkville, VIC, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Vaccination is the most common method used to control infection caused by Methods: This study investigated the effect of immunosuppression induced by either chicken anaemia virus (CAV) or infectious bursal disease virus (IBDV), administered prior to or following vaccination with the Results: Immunosuppression resulted in significant differences in tracheal transcriptional responses compared to immunocompetent groups, irrespective of the timing of infection with CAV or IBDV. Differences in transcription were more pronounced in the IBDV-infected groups than the CAV-infected groups. Functional interrogation of differentially transcribed genes revealed adverse effects of Conclusions: The findings implied that the primary immune response induced post-vaccination and the secondary immune response induced post-challenge with virulent

Indexed as

Bacterial VaccinesImmunity, MucosalMycoplasma gallisepticumMycoplasma InfectionsPoultry DiseasesTracheaAnimalsChicken anemia virusChickensImmunosuppression TherapyInfectious bursal disease virusVaccinationVaccines, AttenuatedBacterial VaccinesVaccines, AttenuatedCAVchicken anaemia virusIBDVimmunosuppressioninfectious burial disease virusMycoplasma gallisepticumRNA-sequencingtrachea

Identifiers

PMID42564117
PMCPMC13442388

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.