Altered cerebral oxygen extraction and metabolism in preterm neonates and the relationship to anemia: A noncontrast MRI study.

Zixuan Lin, Dan Wu, Dengrong Jiang, Hanzhang Lu, Ying Qi

Abstract read

In one paragraph

Article in Annals of the Child Neurology Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zixuan LinKey Laboratory for Biomedical Engineering of Ministry of Education, Department of Biomedical Engineering, College of Biomedical Engineering & Instrument Science Zhejiang University Hangzhou China.

Dan WuKey Laboratory for Biomedical Engineering of Ministry of Education, Department of Biomedical Engineering, College of Biomedical Engineering & Instrument Science Zhejiang University Hangzhou China.

Dengrong JiangThe Russell H. Morgan Department of Radiology & Radiological Science Johns Hopkins University School of Medicine Baltimore Maryland USA.

Hanzhang LuThe Russell H. Morgan Department of Radiology & Radiological Science Johns Hopkins University School of Medicine Baltimore Maryland USA.

Ying QiDepartment of Radiology Shengjing Hospital of China Medical University Shenyang China.ORCID https://orcid.org/0000-0001-9144-6216

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The preterm brain is susceptible to structural injuries, which may be related to an imbalance between blood supply and oxygen metabolism. However, the effect of preterm birth on cerebral oxygen metabolism and its underlying mechanism have not been fully elucidated. The present study measured cerebral oxygen extraction and metabolism using noncontrast magnetic resonance imaging (MRI) methods in preterm neonates and examined its relationship with anemia of prematurity. Methods: Fifty neonates with a gestational age of 28-42 weeks were enrolled. Cerebral oxygen extraction fraction (OEF) and cerebral metabolic rate of oxygen (CMRO Results: We showed that CBF ( Interpretation: These findings demonstrated an altered cerebral oxygen metabolism in preterm brain, suggesting a potential role of MRI-based oxygenation measurement in the assessment of transfusion and intervention for preterm neonates.

Indexed as

anemiacerebral blood flowcerebral oxygen metabolismoxygen extraction fractionpretermTRUST MRI

Identifiers

PMID42563950

DOI10.1002/cns3.20081

PMCPMC13359274

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.