Evidence map›Paper›PMID 42563467›Full record

ArticleMultiple sclerosis (Houndmills, Basingstoke, England)2026

Frequent early cognitive impairment in both pediatric MS and MOGAD.

Michiel Simon Jan Buijze, Sandy Molenaar, Rosa Verkerk, Maud Alida Quist, Willemijn Marije Carolien van der Vlugt, Rinze Frederik Neuteboom

Abstract read
In one paragraph

Article in Multiple sclerosis (Houndmills, Basingstoke, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Michiel Simon Jan BuijzeDivision of Pediatric Neurology, Department of Neurology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands.ORCID 0000-0002-2875-5304
Sandy MolenaarDivision of Pediatric Neurology, Department of Neurology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands.
Rosa VerkerkDepartment of Pediatric Neuropsychology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands.
Maud Alida QuistDivision of Pediatric Neurology, Department of Neurology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands.
Willemijn Marije Carolien van der VlugtDepartment of Pediatric Neuropsychology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands.
Rinze Frederik NeuteboomDivision of Pediatric Neurology, Department of Neurology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands.ORCID 0000-0001-6136-4981

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStudies on early cognitive impairment (CI) in pediatric multiple sclerosis (MS) are heterogeneous and data on pediatric myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) are scarce.

objectivesTo evaluate early cognitive dysfunction in both diseases and delineate disease-specific neurocognitive profiles.

methodsA cross-sectional study of children with MS and MOGAD assessed neurocognition within 2 years after disease onset using a comprehensive test battery. Test results were converted to

resultsSixty-seven participants were analyzed (MS

conclusionIn both pediatric MS and MOGAD, early CI is prevalent with difficulties in complex attention. Visuospatial cognition appears to be an additional vulnerable area for children with MS.

Indexed as

childrencognitive impairmentcognitive profilemultiple sclerosismyelin oligodendrocyte glycoprotein antibody-associated disease

Identifiers

PMID42563467
PMCPMC13646429

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.