Evidence map›Paper›PMID 42563299›Full record

ArticleNeurospine2026

How to Treat Adjacent-Segment Pathology Following Lumbar Fusion Surgery: Decompression Alone or Decompression With Extended Fusion Surgery?

Mohamed Elmekaty, Anders Joelson, Peter Försth, Paul Gerdhem, Nils P Hailer, Yohan Robinson, Anna MacDowall

Abstract read
In one paragraph

Article in Neurospine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Mohamed ElmekatyDepartment of Surgical Sciences, Orthopedics and Hand Surgery, Uppsala University, Uppsala, Sweden. mohamed.elmekaty@uu.se.
Anders JoelsonDepartment of Surgical Sciences, Orthopedics and Hand Surgery, Uppsala University, Uppsala, Sweden.
Peter FörsthDepartment of Surgical Sciences, Orthopedics and Hand Surgery, Uppsala University, Uppsala, Sweden.
Paul GerdhemDepartment of Surgical Sciences, Orthopedics and Hand Surgery, Uppsala University, Uppsala, Sweden.
Nils P HailerDepartment of Surgical Sciences, Orthopedics and Hand Surgery, Uppsala University, Uppsala, Sweden.
Yohan RobinsonInstitute for Clinical Sciences, Gothenburg University, Gothenburg, Sweden.
Anna MacDowallDepartment of Surgical Sciences, Orthopedics and Hand Surgery, Uppsala University, Uppsala, Sweden.

Funding

Central Sweden Regional Research CouncilRegion Örebro County
6 · The paper itself

Abstract

objectiveThis study aims to compare the risk of subsequent surgery following surgical treatment of clinical adjacent-segment pathology (CASP) after lumbar fusion, specifically evaluating decompression alone versus decompression with extension of the fusion.

methodsUsing the Swespine registry, we included patients who had surgical treatment for CASP following index lumbar fusion surgery, 1997-2019. The cohort was divided according to CASP treatment: decompression alone or decompression with extended fusion. A comparison of subsequent surgeries was made with Kaplan-Meier analysis and Cox regressions adjusted for potential confounders (age, sex, body mass index, smoking status, number of operated levels at CASP surgery, number of fused levels at index fusion surgery, and diagnosis for CASP surgery).

resultsA total of 2,521 patients were included, 1,176 (47%) in the decompression-group and 1,345 (53%) in the extended fusion group and the mean follow-up was 6.1±4.4 years. Mean age at CASP surgery was 61 years and 1,588 (63%) were females. The median time to subsequent surgery was 1.7 years (range, 0.9-3.7 years). Kaplan-Meier-estimated probability of subsequent surgeries at 5 years was 18% (95% confidence interval [CI], 15%-20%) for the decompression-group and 25% (95% CI, 22%-27%) for the extended fusion group. The hazard ratio was 1.26 (95% CI, 1.02-1.56; p=0.032) for those with extended fusion.

conclusionExtension of fusion for CASP was associated with significantly higher risk of subsequent surgery, but causality should be interpreted with caution as radiographic information on instability, deformity, or foraminal stenosis could not be verified.

Indexed as

Adjacent-segment pathologyDecompression surgeryExtended fusionLumbar fusionRegistry studyReoperationSpine surgery

Identifiers

PMID42563299
PMCPMC13448034

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.