Evidence map›Paper›PMID 42563273›Full record

ArticleVeterinary surgery : VS2026

Influence of intra-articular injectate volume on joint surface coverage and leakage following canine elbow arthroscopy: A cadaveric study.

Erin Smith, Sarah Stark, Shelby Boynton, Wanda Gordon-Evans

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Article in Veterinary surgery : VS, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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5 · Who and what money

Authors and funding

4 authors.

Erin SmithUniversity of Minnesota, Department of Veterinary Clinical Sciences, St. Paul, Minnesota, USA.ORCID https://orcid.org/0009-0005-8473-4136
Sarah StarkUniversity of Minnesota, Department of Veterinary Clinical Sciences, St. Paul, Minnesota, USA.
Shelby BoyntonUniversity of Minnesota, Department of Veterinary Clinical Sciences, St. Paul, Minnesota, USA.
Wanda Gordon-EvansUniversity of Minnesota, Department of Veterinary Clinical Sciences, St. Paul, Minnesota, USA.ORCID https://orcid.org/0000-0003-1356-8327

Funding

Tata Orthopedic Research Endowment
6 · The paper itself

Abstract

objectiveTo determine whether reduced intra-articular (IA) injection volumes provide complete synovial surface coverage while minimizing leakage following canine elbow arthroscopy. STUDY

designRandomized cadaveric study. ANIMALS: Forty elbow joints from 20 canine cadavers weighing >15 kg.

methodsStandard medial elbow arthroscopy was performed with portals placed under arthroscopic guidance. The egress portal was created along the caudal margin of the medial epicondylar ridge, directed toward the anconeal process. A third, craniomedial instrument portal was created approximately 1 cm cranial to the camera portal. Following arthroscopy, India ink-volume-matched to whole, half, or quarter of a 0.5 mg/kg ropivacaine dose (0.75% concentration)-was injected via the egress portal. Each joint underwent 10 passive flexion-extension cycles before dissection. A masked investigator (ES) qualitatively assessed synovial surface coverage (100%, 75%-99%, 50%-74%, 25%-49%, 0%-24%) and leakage severity (mild, moderate, severe). Portal placement attempts, cadaver age, and bodyweight were recorded.

resultsMean cadaver age was 9.3 years (range: 1-16 years), and mean weight was 29.9 kg (range: 17.9-43.6 kg). Complete (100%) synovial surface coverage was observed in all 40 elbows, including those receiving quarter-dose injections. Leakage occurred in every dose group, with a similar distribution of mild, moderate, and severe categories. Portal placement was successful on the first attempt in 32 elbows (80%) and the second attempt in eight elbows (20%).

conclusionReduced IA injection volumes achieved complete synovial surface coverage but did not reduce leakage severity. CLINICAL SIGNIFICANCE: Reduced intra-articular injection volumes were sufficient to achieve complete synovial surface coverage in this model, suggesting potential flexibility in clinical dosing strategies. Nonetheless, extravasation occurred at all tested volumes, reinforcing that some leakage should be expected in practice.

Indexed as

ArthroscopyForelimbJointsAnimalsCadaverDogsFemaleInjections, Intra-ArticularRopivacaineRopivacaine

Identifiers

PMID42563273
PMCPMC13643635

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.