Evidence map›Paper›PMID 42563210›Full record

ReviewComprehensive reviews in food science and food safety2026

The Chemistry of Time: Flavor Evolution and Functional Health Benefits in Aged Tea.

Yan Liu, Rongbosen Yue, Yucheng Zou, Sibo Zhao, Jielin Jiang, Liyong Luo, Zhonghua Liu, Liang Zeng

Abstract readReview
In one paragraph

Review in Comprehensive reviews in food science and food safety, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yan LiuIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City/College of Food Science, Southwest University, Chongqing, China.ORCID https://orcid.org/0000-0003-3677-9290
Rongbosen YueIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City/College of Food Science, Southwest University, Chongqing, China.
Yucheng ZouSchool of Food and Biological Engineering, Jiangsu University, International Joint Research Laboratory of Intelligent Agriculture and Agri-products Processing (Jiangsu University), Zhenjiang, Jiangsu, China.
Sibo ZhaoIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City/College of Food Science, Southwest University, Chongqing, China.
Jielin JiangChongqing Key Laboratory of Speciality Food Co-Built by Sichuan and Chongqing, Chongqing, China.
Liyong LuoIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City/College of Food Science, Southwest University, Chongqing, China.
Zhonghua LiuKey Laboratory of Tea Science of Ministry of Education, Hunan Agricultural University, Changsha, Hunan, China.
Liang ZengIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City/College of Food Science, Southwest University, Chongqing, China.ORCID https://orcid.org/0000-0003-3860-7724

Funding

China Postdoctoral Science Foundation 2026T190798Chongqing Modern Agricultural Industry Technology System CQMAITS202608
6 · The paper itself

Abstract

Aged teas (dark, white, and heavily baked Oolong) undergo significant transformations during storage, yet the industry remains constrained by a lack of scientific standardization. This review dissects how storage conditions influence flavor, health benefits, and constituent changes. It further evaluates vintage prediction and accelerated aging technologies, proposing the integration of Industry 5.0 to modernize the sector. Mechanistically, aging is driven by enzymatic oxidation, nonenzymatic reactions, and microbial metabolism. The degradation of flavanols drives the reduction of bitterness and astringency, while the formation of polymeric catechins and N-ethyl-2-pyrrolidinone-substituted flavanols (EPSFs) serves as the key marker of aging. Additionally, the synergistic balance between methoxybenzenes and accumulating volatiles, such as woody/herbal compounds among others, drives the formation of the aged aroma. Regarding environmental factors, temperature, humidity, and microbial participation drive material transformation. While high-temperature/humidity environments can accelerate transformation, they may compromise quality. In terms of health benefits, components formed after aging (e.g., EPSFs and theabrownins) demonstrate advantages in regulating gut microbiota homeostasis and improving glucolipid metabolism. Notably, aging time is not linearly positively correlated with flavor and health benefits, but rather possesses an optimal window. Although vintage prediction models have been developed, their generalization ability across batches of teas remains to be improved. In terms of accelerated aging, ultraviolet radiation and high-voltage pulsed electric fields can induce sensory profiles closer to naturally aged tea in a shorter time than microbial inoculation and wet-heat treatments. Concurrently, the introduction of Industry 5.0 paradigms may provide potential for addressing vintage fraud, achieving precise quality control, and promoting green development in the industry.

Indexed as

Food StorageTasteTeaFood HandlingHumansTeaAged teaAgingDark teaOolong teaVintageWhite tea

Identifiers

PMID42563210
PMCPMC13447706

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.