Evidence map›Paper›PMID 42563166›Full record

ArticleCost effectiveness and resource allocation : C/E2026

Cost-effectiveness of community-based interventions for type 2 diabetes management in Indonesia: a time-horizon sensitivity analysis.

Aalbrecht A Irawan, Nursanti Anggriani, Yudhie Andriyana, Rizky Abdulah

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Article in Cost effectiveness and resource allocation : C/E, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Aalbrecht A IrawanDoctoral Program in Mathematics, Faculty of Mathematics and Natural Science, Universitas Padjadjaran, Jalan Ir Soekarno KM 21, West Java, 45363, Sumedang, Indonesia.
Nursanti AnggrianiDepartment of Mathematics, Faculty of Mathematics and Natural Science, Universitas Padjadjaran, Jalan Ir Soekarno KM 21, West Java, 45363, Sumedang, Indonesia. nursanti.anggriani@unpad.ac.id.
Yudhie AndriyanaDepartment of Statistics, Faculty of Mathematics and Natural Science, Universitas Padjadjaran, Jalan Ir Soekarno KM 21, West Java, 45363, Sumedang, Indonesia.
Rizky AbdulahDepartment of Pharmacological and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Jalan Ir Soekarno KM 21, West Java, 45363, Sumedang, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundType 2 Diabetes Mellitus (T2DM) imposes a severe economic burden on Indonesia's Social Health Insurance Administration Body (BPJS Kesehatan), driven predominantly by expensive late-stage complications. While the Prolanis program offers community-based prevention, a lack of long-term economic forecasting hinders optimal resource allocation among its core interventions. To address this gap, this study aims to evaluate community-based intervention strategies to determine which approach is the most cost-effective for long-term T2DM management in Indonesia.

methodsWe developed a deterministic linear compartmental state-transition model to forecast the 25-year epidemiological and economic impacts of six intervention strategies derived from three Prolanis pillars: health education, physical activity, and lifestyle modification. The model integrated an economic resource allocation framework, Indonesian epidemiology data, and a 3.8-fold complication cost penalty multiplier for complication states. Cost-effectiveness was evaluated from a healthcare payer perspective using the Incremental Cost-Effectiveness Ratio (ICER) and Time-Horizon Sensitivity Analysis.

resultsOver 25 years, the Lifestyle Modification intervention emerged as the dominant strategy compared to baseline care. It generated the highest increase in the managed T2DM population while incurring the lowest total systemic cost. ICER analyses demonstrated that Lifestyle Modification strictly dominated individual and combined promotive activities, which were subject to severe budgetary restrictions due to their high delivery cost-weights. Furthermore, temporal analysis confirmed that Lifestyle Modification achieves systemic net savings rapidly by Year 5. By Year 25, it resulted in projected cumulative net savings of 19.22 trillion IDR under the 3% base-case discount rate, with sensitivity analyses confirming robust dominance across 0% (27.61 trillion IDR savings) and 5% (15.48 trillion IDR savings) discount rates.

conclusionLifestyle Modification is the most economically dominant community-based intervention for managing T2DM in Indonesia. To avert the financial penalties of downstream complications, policymakers should strategically rebalance the Prolanis capitation budget to prioritize proactive, monitoring-driven lifestyle interventions.

Indexed as

Diabetes management strategiesHealth policyLifestyle modificationMathematic modelingResource allocation

Identifiers

PMID42563166
PMCPMC13450512

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.