ArticleMethods in molecular biology (Clifton, N.J.)2026
Synthesis of Environmentally Friendly Heavy-Metal-Free AgInS
Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Luminescent semiconductor nanocrystals, also known as quantum dots (QDs), have had a major impact on applications of optical techniques in the life sciences, such as biosensing and bioimaging. Their unique optical properties, such as broad absorption bands with high molar extinction coefficients, together with their narrow size-dependent photoluminescence (PL) bands, high PL quantum yields (QYs), and a high photostability, are unique advantages for QDs as optical reporters in immunoassays, theranostics, in vitro/in vivo imaging, and flow cytometry. This also laid the foundation for numerous applications of optical multiplexing and barcoding. The most popular QD element compositions are based on heavy-metal elements, such as cadmium or lead, which pose a high toxic risk and are meanwhile restricted in Europe by REACH regulation. Increasing environmental concerns and the growing interest in and need for nanomaterials accessible by sustainable synthesis routes triggered the search for more eco-friendly QDs in the last years. Promising heavy-metal free candidates are ternary AgInS
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