Evidence map›Paper›PMID 42563012›Full record

ArticleJournal of computer-aided molecular design2026

Ligand-based pharmacophore modeling for the discovery of Na

Martina Piga, Peter Lukacs, Krisztina Pesti, György Várady, Zoltan Varga, Nace Zidar, Tihomir Tomašič

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of computer-aided molecular design, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Martina PigaFaculty of Pharmacy, University of Ljubljana, Aškerčeva cesta 7, Ljubljana, 1000, Slovenia.ORCID 0009-0006-8549-3386
Peter LukacsAgricultural Institute, Centre for Agricultural Research, Martonvásár, Hungary.
Krisztina PestiAgricultural Institute, Centre for Agricultural Research, Martonvásár, Hungary.
György VáradyInstitute of Molecular Life Sciences, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary.
Zoltan VargaDepartment of Biophysics and Cell Biology, Faculty of Medicine, University of Debrecen, Egyetem ter1, Debrecen, 4032, Hungary.
Nace ZidarFaculty of Pharmacy, University of Ljubljana, Aškerčeva cesta 7, Ljubljana, 1000, Slovenia.
Tihomir TomašičFaculty of Pharmacy, University of Ljubljana, Aškerčeva cesta 7, Ljubljana, 1000, Slovenia. tihomir.tomasic@ffa.uni-lj.si.ORCID 0000-0001-5534-209X

Funding

Nemzeti Kutatási Fejlesztési és Innovációs Hivatal 2025-1.2.4-TÉT-2025-00007The Slovenian Research and Innovation Agency P1-0208
6 · The paper itself

Abstract

Voltage-gated sodium channel Na

Indexed as

NAV1.7 Voltage-Gated Sodium ChannelSulfonamidesVoltage-Gated Sodium Channel BlockersDrug DiscoveryHumansLigandsMolecular Docking SimulationPharmacophoreLigandsNAV1.7 Voltage-Gated Sodium ChannelSCN9A protein, humanSulfonamidesVoltage-Gated Sodium Channel BlockersNaV1.7 inhibitorsPharmacophore modelSelectivityVirtual screeningVoltage-gated sodium channel

Identifiers

PMID42563012
PMCPMC13447489

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.