ArticleEuropean journal of clinical nutrition2026
Global leadership initiative on malnutrition criteria using different muscle mass assessment methods in hemodialysis patients: Links to physical performance, quality of life, and clinical outcomes.
Article in European journal of clinical nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectivesMalnutrition is frequent in maintenance hemodialysis (MHD). We aimed to validate the Global Leadership Initiative on Malnutrition (GLIM) criteria using different muscle mass assessment methods and evaluate their associations with nutritional biomarkers, functional status, quality of life, and mortality. SUBJECTS/
methodsThis prospective study included 218 MHD outpatients (63% male; mean age 70.6 ± 12.2 years). Muscle mass was assessed using bioimpedance analysis (BIA), mid-arm muscle circumference (MAMC), and calf circumference (CC). Serum biomarkers, handgrip strength, gait speed, and nutritional scores (Malnutrition Inflammation Score [MIS], Geriatric Nutritional Risk Index [GNRI]) were obtained. Malnutrition was defined as MIS > 10. Associations with SF-36 scales and survival were analysed.
resultsMalnutrition prevalence was 26.1% with BIA-based GLIM, 25.2% with MAMC-based GLIM, and 27.1% with CC. BIA-based GLIM correlated with albumin, MIS, GNRI, phase angle, handgrip strength, and gait speed. MAMC-based GLIM showed similar associations except for gait speed. CC-based GLIM correlated with albumin and GNRI. Agreement with MIS was fair (κ = 0.31-0.35). All GLIM variants showed high specificity but low sensitivity. Only BIA- and MAMC-based GLIM were associated with reduced quality of life. BIA-based GLIM predicted higher mortality (HR 1.70, 95% CI 1.01-2.85), and CC-based GLIM showed a stronger association (HR 2.94, 95% CI 1.41-6.14). MAMC-based GLIM showed a nonsignificant trend.
conclusionsGLIM demonstrated fair agreement with MIS, high specificity, and meaningful concurrent validity. MAMC- and CC-based GLIM provided practical alternatives to BIA. These findings support further validation of anthropometric GLIM variants in diverse MHD populations.
Identifiers
42563008What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.