Evidence map›Paper›PMID 42562957›Full record

ArticleArchives of orthopaedic and trauma surgery2026

Patient mortality exceeds implant revision risk with equivalent survival following unicompartmental versus total knee arthroplasty in octogenarians.

Matteo Innocenti, Filippo Leggieri, Marta Massenzi, Davide Stimolo, Mustafa Akkaya, Fabrizio Matassi, Roberto Civinini

Abstract readComparative Study
In one paragraph

Article in Archives of orthopaedic and trauma surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Matteo InnocentiDepartment of Clinical Orthopaedics, University of Florence, Florence, Italy.
Filippo LeggieriDepartment of Clinical Orthopaedics, University of Florence, Florence, Italy. filippoleggieri@icloud.com.ORCID https://orcid.org/0009-0007-1289-8849
Marta MassenziDepartment of Clinical Orthopaedics, University of Florence, Florence, Italy.
Davide StimoloDepartment of Clinical Orthopaedics, University of Florence, Florence, Italy.
Mustafa AkkayaDepartment of Orthopaedics and Traumatology, Yüksek İhtisas Üniversitesi, Ankara, Turkey.
Fabrizio MatassiDepartment of Clinical Orthopaedics, University of Florence, Florence, Italy.
Roberto CivininiDepartment of Clinical Orthopaedics, University of Florence, Florence, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhile traditional surgical decision-making emphasizes long-term implant survivorship for octogenarians knee reconstruction, this paradigm may be inappropriate when patient mortality risk substantially exceeds revision risk. This study compared mid-term mortality between unicompartmental knee arthroplasty (UKA) and total knee arthroplasty (TKA) in octogenarians, hypothesizing that implant type would not significantly influence patient survival.

methodsA retrospective cohort study was conducted on 238 consecutive octogenarian patients (age ≥ 80 years) who underwent primary knee arthroplasty at a single tertiary orthopaedic center between January 2018 and December 2020. Patients with revision arthroplasty, fracture, tumor, inflammatory arthropathy, or incomplete data were excluded. The primary outcome was all-cause mortality at minimum 5-year follow-up. Secondary outcomes included age-stratified mortality (80-84, 85-89, ≥ 90 years) and identification of independent mortality predictors. Statistical analyses included independent t-tests, chi-square/Fisher's exact tests, standardized mean differences, and multivariable logistic regression adjusting for age, follow-up duration, and registry year.

resultsOf 238 patients, 185 (77.7%) underwent TKA and 53 (22.3%) underwent UKA. Overall mortality was 35.3% (84/238): 33.5% in TKA versus 41.5% in UKA (OR = 1.41, 95% CI: 0.75-2.63, p = 0.329). Age-stratified mortality showed no significant differences: 80-84 years (31.2% TKA vs. 37.2% UKA, p = 0.467), 85-89 years (42.3% vs. 50.0%, p = 1.000). Multivariable analysis identified age as the only significant mortality predictor (adjusted OR = 1.16 per year, 95% CI: 1.03-1.32, p = 0.013), while implant type was not associated with mortality (adjusted OR = 1.40, 95% CI: 0.72-2.73, p = 0.319). Patient mortality exceeded registry-reported revision rates 3-5 fold.

conclusionsIn octogenarians, patient mortality substantially exceeds implant revision risk, with no significant difference between UKA and TKA. Surgeons should prioritize patient-specific clinical indications over theoretical implant durability concerns when selecting procedures in this population. LEVEL OF EVIDENCE: III.

Indexed as

Arthroplasty, Replacement, KneeKnee ProsthesisReoperationAged, 80 and overFemaleHumansMaleOctogenariansProsthesis FailureRetrospective StudiesCompeting riskImplant survivorshipMortalityOctogenariansTotal knee arthroplastyUnicompartmental knee arthroplasty

Identifiers

PMID42562957
PMCPMC13447535

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.