Evidence map›Paper›PMID 42562571›Full record

ArticleGenes & development2026

Adaptation of eukaryotic membrane homeostasis to species-specific cellular lipid landscapes.

Elisa Gomez-Gil, Paolo Guerra, Ying Gu, Sherman Foo, Benedicte Billard, Gabor Balogh, Maria Peter, Snezhana Oliferenko

Abstract read
In one paragraph

Article in Genes & development, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Elisa Gomez-GilRandall Centre for Cell and Molecular Biophysics, School of Basic and Medical Biosciences, King's College London, London SE1 1UL, United Kingdom.ORCID http://orcid.org/0000-0001-9157-2028
Paolo GuerraRandall Centre for Cell and Molecular Biophysics, School of Basic and Medical Biosciences, King's College London, London SE1 1UL, United Kingdom.ORCID http://orcid.org/0000-0002-2291-3834
Ying GuRandall Centre for Cell and Molecular Biophysics, School of Basic and Medical Biosciences, King's College London, London SE1 1UL, United Kingdom.ORCID http://orcid.org/0000-0003-1630-0502
Sherman FooRandall Centre for Cell and Molecular Biophysics, School of Basic and Medical Biosciences, King's College London, London SE1 1UL, United Kingdom.ORCID http://orcid.org/0000-0001-7204-7172
Benedicte BillardUniversité Côte d'Azur, Centre National de la Recherche Scientifique, Institut National de la Santé et de la Recherche Médicale, Nice 06100, France.
Gabor BaloghInstitute of Biochemistry, Hungarian Research Network (HUN-REN) Biological Research Centre, Szeged H-6726, Hungary.ORCID http://orcid.org/0000-0002-4565-6850
Maria PeterInstitute of Biochemistry, Hungarian Research Network (HUN-REN) Biological Research Centre, Szeged H-6726, Hungary.ORCID http://orcid.org/0000-0003-0362-6933
Snezhana OliferenkoRandall Centre for Cell and Molecular Biophysics, School of Basic and Medical Biosciences, King's College London, London SE1 1UL, United Kingdom; snezhana.oliferenko@kcl.ac.uk.ORCID http://orcid.org/0000-0002-8138-6851

Funding

Wellcome Trust CC0102
6 · The paper itself

Abstract

The physicochemical properties of biological membranes must be maintained within a range compatible with cellular physiology. In the face of external perturbations, membrane lipid homeostasis mechanisms sense and control membrane features. How such mechanisms evolve to function in organisms with different cellular lipid make-up is unknown. Here, we address this fundamental question by exploiting the natural divergence in membrane lipid composition between the related fission yeasts

Indexed as

Adaptation, PhysiologicalCell MembraneHomeostasisLipid MetabolismMembrane LipidsSchizosaccharomycesGene Expression Regulation, FungalLipidomicsSchizosaccharomyces pombe ProteinsSpecies SpecificityStearoyl-CoA Desaturasedelta-9 fatty acid desaturaseMembrane LipidsSchizosaccharomyces pombe ProteinsStearoyl-CoA Desaturaseevolutionfission yeastshomeostasismembrane

Identifiers

PMID42562571
PMCPMC13532661

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.