Evidence map›Paper›PMID 42562395›Full record

ArticleBone & joint open2026

Patellofemoral outcomes after kinematic versus mechanical alignment in primary total knee arthroplasty : a focused scoping review of head-to-head comparative studies.

Seikai Toyooka, Yutoshi Osaki, Noriaki Arai, Hirotaka Kawano, Takumi Nakagawa

Abstract read
In one paragraph

Article in Bone & joint open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Seikai ToyookaDepartment of Orthopaedic Surgery, Teikyo University School of Medicine, Tokyo, Japan.ORCID 0000-0002-3503-0360
Yutoshi OsakiDepartment of Orthopaedic Surgery, Teikyo University School of Medicine, Tokyo, Japan.
Noriaki AraiDepartment of Orthopaedic Surgery, Teikyo University School of Medicine, Tokyo, Japan.
Hirotaka KawanoDepartment of Orthopaedic Surgery, Teikyo University School of Medicine, Tokyo, Japan.
Takumi NakagawaDepartment of Orthopaedic Surgery, Teikyo University School of Medicine, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: Concerns persist that kinematic alignment (KA) in primary total knee arthroplasty (TKA) may adversely affect the patellofemoral (PF) joint, because most contemporary components were developed under mechanical alignment (MA) principles. This focused scoping review mapped head-to-head comparative clinical evidence on PF outcomes after KA versus MA TKA, and identified key evidence gaps relevant to clinical decision-making. Methods: A focused scoping review was conducted. PubMed/MEDLINE, the Cochrane Library, and CINAHL were searched from inception to 15 January 2026. We included head-to-head comparative studies directly comparing KA and MA in primary TKA that reported at least one PF-related outcome. PF outcomes were mapped into three domains: 1) PF symptoms and PF-specific patient-reported outcome measures (PROMs); 2) PF-related interventions and complications; and 3) PF imaging/radiological measures. Findings were synthesized descriptively. Results: A total of 12 studies met the inclusion criteria. Domain A was addressed by only one study and was insufficient for definitive conclusions. Domain B was addressed by six studies; no consistent signal of higher PF-related interventions/complications with KA was identified, and several studies reported numerically fewer PF-related procedures with KA, including lateral retinacular release. Domain C was addressed by ten studies and showed heterogeneous imaging findings; when PF radiological differences were observed, they were not consistently accompanied by worse symptoms or higher PF-related intervention rates. Postoperative rotational alignment was inconsistently assessed. Conclusion: Current head-to-head comparative evidence is insufficient to determine the definitive PF-specific clinical impact of KA versus MA, mainly because PF-specific PROMs are rarely reported. Although no consistent harm signal was identified, this should not be interpreted as evidence of equivalence. This review primarily defines current evidence gaps, including the need for prespecified PF-specific PROMs, systematic rotational verification, consistent reporting of PF-related interventions/complications, and longer follow-up.

Identifiers

PMID42562395
PMCPMC13447007

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.