Evidence map›Paper›PMID 42561915›Full record

ArticleCell2026

A complete genome for the common marmoset.

Prajna Hebbar, Tamara Potapova, Hailey Loucks, Karina Ray, Murillo F Rodrigues, Fedor Ryabov, Joanna Malukiewicz, DongAhn Yoo, Leonardo Gomes de Lima, Annat Haber and 32 more

Abstract read
In one paragraph

Article in Cell, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Census and genetic analysis of the United States marmoset population.bioRxiv : the preprint server for biology · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

42 authors.

Prajna HebbarUC Santa Cruz Genomics Institute, University of California, Santa Cruz, Santa Cruz, CA 95060, USA. Electronic address: pnhebbar@ucsc.edu.
Tamara PotapovaStowers Institute for Medical Research, Kansas City, MO 64110, USA.
Hailey LoucksUC Santa Cruz Genomics Institute, University of California, Santa Cruz, Santa Cruz, CA 95060, USA.
Karina RayDivision of Genetics, Oregon National Primate Research Center, Beaverton, OR 97006, USA.
Murillo F RodriguesDivision of Genetics, Oregon National Primate Research Center, Beaverton, OR 97006, USA.
Fedor RyabovCentre for Biomedical Research and Technology, HSE University, Moscow, Russia; The Center for Bio- and Medical Technologies, Moscow, Russia.
Joanna MalukiewiczPrimate Genetics Laboratory, German Primate Center, Leibniz Institute for Primate Research, Göttingen, Germany; Instituto de Medicina Tropical de São Paulo, Universidade de São Paulo, São Paulo, SP, Brazil.
DongAhn YooDepartment of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA.
Leonardo Gomes de LimaStowers Institute for Medical Research, Kansas City, MO 64110, USA.
Annat HaberThe Jackson Laboratory, Bar Harbor, ME 04609, USA.
Sonal KumarThe Jackson Laboratory, Bar Harbor, ME 04609, USA; Graduate School of Biomedical Sciences, Tufts University, Boston, MA 02111, USA.
Swati BanerjeeDepartment of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
Matthew BorchersStowers Institute for Medical Research, Kansas City, MO 64110, USA.
Gage H GarciaDepartment of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA.
Joshua GardnerUC Santa Cruz Genomics Institute, University of California, Santa Cruz, Santa Cruz, CA 95060, USA.
Stephanie HachemDepartment of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
Harrison D HeathUC Santa Cruz Genomics Institute, University of California, Santa Cruz, Santa Cruz, CA 95060, USA.
Seung Kwon HaDepartment of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
Mira MastorasUC Santa Cruz Genomics Institute, University of California, Santa Cruz, Santa Cruz, CA 95060, USA.
Brandy McNultyUC Santa Cruz Genomics Institute, University of California, Santa Cruz, Santa Cruz, CA 95060, USA.
Julian MenendezUC Santa Cruz Genomics Institute, University of California, Santa Cruz, Santa Cruz, CA 95060, USA.
Katherine M MunsonDepartment of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA.
Karol PalDepartment of Biology, Pennsylvania State University, University Park, PA 16802, USA.
JungEun ParkDepartment of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
Simon PlöschPrimate Genetics Laboratory, German Primate Center, Leibniz Institute for Primate Research, Göttingen, Germany.
Christian RoosPrimate Genetics Laboratory, German Primate Center, Leibniz Institute for Primate Research, Göttingen, Germany.
William E SeligmannUC Santa Cruz Genomics Institute, University of California, Santa Cruz, Santa Cruz, CA 95060, USA.
Valery ShepelevInstitute of Molecular Genetics, Moscow, Russia.
Catrina SpruceThe Jackson Laboratory, Bar Harbor, ME 04609, USA.
Ivo ViolichUC Santa Cruz Genomics Institute, University of California, Santa Cruz, Santa Cruz, CA 95060, USA.
Lutz WalterPrimate Genetics Laboratory, German Primate Center, Leibniz Institute for Primate Research, Göttingen, Germany.
Kateryna D MakovaDepartment of Biology, Pennsylvania State University, University Park, PA 16802, USA.
Amantha ThathiahDepartment of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
Stacey J Sukoff RizzoDepartment of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
Afonso C SilvaDepartment of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
Gregory W CarterThe Jackson Laboratory, Bar Harbor, ME 04609, USA; Graduate School of Biomedical Sciences, Tufts University, Boston, MA 02111, USA.
Karen H MigaUC Santa Cruz Genomics Institute, University of California, Santa Cruz, Santa Cruz, CA 95060, USA.
Evan E EichlerDepartment of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA; Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA.
Donald F ConradDivision of Genetics, Oregon National Primate Research Center, Beaverton, OR 97006, USA.
Jennifer L GertonStowers Institute for Medical Research, Kansas City, MO 64110, USA.
Ivan A AlexandrovDepartment of Human Molecular Genetics and Biochemistry, Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.
Benedict PatenUC Santa Cruz Genomics Institute, University of California, Santa Cruz, Santa Cruz, CA 95060, USA. Electronic address: bpaten@ucsc.edu.

Funding

Upgrade of confocal microscopy at the Oregon National Primate Research CenterP51OD011092 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI Bonnie J. Nagel · 2012 to 2026
$203.9M
Veterinary and Colony Management CoreU19AG074866 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Afonso C Silva · 2022 to 2026
$44.9M
The AnVIL Data Ecosystem DACReS SupplementU24HG010262 · NHGRI · BROAD INSTITUTE, INC. · PI Robert J Carroll, Jonathan Lawson · 2018 to 2026
$40.5M
Sequence and Assembly of Segmental DuplicationsR01HG002385 · NHGRI · UNIVERSITY OF WASHINGTON · PI Evan Eichler · 2001 to 2026
$13.3M
Dockstore: The Community Platform for Reproducible Biomedical Workflows and ApplicationsU24HG011853 · NHGRI · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI Jonathan Lawson, Benedict Paten · 2021 to 2026
$5.7M
Regulation of gamma-secretase function in Alzheimer's diseaseR01AG058851 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Amantha Thathiah · 2018 to 2026
$4.0M
Comprehensive, Flexible and FAIR Tools for the HuBMAP HIVEOT2OD026682 · OD · CARNEGIE-MELLON UNIVERSITY · PI PATEN, BENEDICT, RUFFALO, MATTHEW · 2018 to 2021
$3.4M
The construction and utility of reference pan-genome graphsU01HG010961 · NHGRI · DANA-FARBER CANCER INST · PI LI, HENG, PATEN, BENEDICT · 2020 to 2023
$3.2M
Non-B DNA and Genome EvolutionR35GM151945 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI KATERYNA MAKOVA · 2024 to 2026
$2.6M
Maintaining the integrity of a genomeR01CA266339 · NCI · STOWERS INSTITUTE FOR MEDICAL RESEARCH · PI JENNIFER L GERTON · 2022 to 2026
$1.9M
UCSC Graduate Program in Genome SciencesT32HG012344 · NHGRI · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI Angela Norie Brooks, Christopher Vollmers · 2022 to 2026
$1.5M
New methods for studying thousands of complete human and vertebrate genomesR01HG014490 · NHGRI · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI Benedict Paten, Yatish Turakhia · 2025 to 2026
$1.2M
NCI NIH HHS R01 CA266339NCI NIH HHS R50 CA305001NHGRI NIH HHS R01 HG002385NHGRI NIH HHS R01 HG014490NHGRI NIH HHS T32 HG012344NHGRI NIH HHS U01 HG010961NHGRI NIH HHS U24 HG010262NHGRI NIH HHS U24 HG011853NIA NIH HHS R01 AG058851NIA NIH HHS U19 AG074866NIGMS NIH HHS R35 GM151945NIH HHS OT2 OD026682NIH HHS P51 OD011092NIH HHS S10 OD028511
6 · The paper itself

Abstract

The common marmoset is a New World monkey widely used to study primate evolution and human disease. We present a telomere-to-telomere (T2T) reference assembly for the species, plus three near-T2T haplotypes. These resolve previously inaccessible regions, including the centromeres, sex chromosomes, subterminal satellites, acrocentric chromosomes, and the major histocompatibility complex (MHC). We find marmoset centromeres carry dimeric alpha satellites with chromosomal specificity, flanked by inactive layers interpreted as ancestral centromere remnants. We assemble gene-poor, satellite-rich short arms of the acrocentrics and find that most can harbor rDNA and all share pseudo-homolog regions (PHRs). PHR-sharing chromosomes also share closely related centromeric satellites, consistent with a model of ongoing rDNA-facilitated recombinational exchange between heterologous chromosomes. We further identify over 500 marmoset-lineage-specific transcribed genes with previously unknown transcript models or expansions. These resources, along with a preliminary pangenome, improve the utility of the marmoset as a model organism and address gaps in primate genome evolution.

Indexed as

CallithrixGenomeAnimalsCentromereDNA, SatelliteEvolution, MolecularFemaleHumansTelomereDNA, Satelliteacrocentric chromosomescentromeric satellitescommon marmosetgenome assemblyMHCribosomal DNAsegmental duplicationstelomere-to-telomere

Identifiers

PMID42561915
PMCPMC13456403

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.