Evidence map›Paper›PMID 42561592›Full record

ArticleEnvironment international2026

Ambient fine particulate matter components and liver fat and stiffness in youth: metabolic vulnerability in PNPLA3 risk carriers.

Haonan Li, Rachel B Schenker, Katherine M Marquess, Devendra Paudel, Cuauhtemoc B Ramirez, Fredrick Lurmann, Mengyuan Ren, Cholsoon Jang, Hooman Allayee, Jiawen Liao and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environment international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Haonan LiDepartment of Environmental Health and Engineering, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Rachel B SchenkerDivision of Pediatric Gastroenterology, University of California, Los Angeles, Los Angeles, CA, USA.
Katherine M MarquessDepartment of Environmental Health and Engineering, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Devendra PaudelDepartment of Environmental Health and Engineering, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Cuauhtemoc B RamirezDepartment of Biological Chemistry, University of California Irvine School of Medicine, Irvine, CA, USA.
Fredrick LurmannSonoma Technology, Inc., Petaluma, CA, USA.
Mengyuan RenGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Cholsoon JangDepartment of Biological Chemistry, University of California Irvine School of Medicine, Irvine, CA, USA.
Hooman AllayeeDepartment of Medicine, Division of Cardiology, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA, USA.
Jiawen LiaoDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Zhanghua ChenDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Michael I GoranDepartment of Pediatrics, The Saban Research Institute, Children's Hospital Los Angeles, and the Department of Psychiatry at the Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Tanya L AldereteDepartment of Environmental Health and Engineering, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA. Electronic address: taldere1@jhu.edu.

Funding

Southern California Center for Chronic Health Disparities in Latino Children and Families.P50MD017344 · NIMHD · CHILDREN'S HOSPITAL OF LOS ANGELES · PI GORAN, MICHAEL ISAAC · 2021 to 2025
$27.8M
Traning Program in Environmental Health SciencesT32ES007141 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI Marsha Wills-Karp · 1985 to 2026
$22.2M
Southern California Children's Environmental Health Center (SC-CEHC)P01ES022845 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MCCONNELL, ROB S · 2013 to 2018
$4.0M
Nutrigenetic Intervention to Reduce Liver Fat in Hispanics - SupplementR01MD010358 · NIMHD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GORAN, MICHAEL ISAAC · 2016 to 2019
$3.3M
Perfluoroalkyl Substances and the Gut Microbiome and Fecal Metabolome: Implications for Obesity Risk in Hispanic ChildrenR01ES035035 · NIEHS · UNIVERSITY OF COLORADO · PI Tanya Lynn Alderete · 2023 to 2026
$2.6M
Pre- and Postnatal Exposure to Air Pollutants and the Gut Microbiome: Implications for Brain Development in Early and Mid-ChildhoodR01ES035056 · NIEHS · UNIVERSITY OF COLORADO · PI Tanya Lynn Alderete, BRADLEY S PETERSON · 2024 to 2026
$2.1M
NIEHS NIH HHS P01 ES022845NIEHS NIH HHS R01 ES035035NIEHS NIH HHS R01 ES035056NIEHS NIH HHS T32 ES007141NIMHD NIH HHS P50 MD017344NIMHD NIH HHS R01 MD010358
6 · The paper itself

Abstract

BACKGROUND &

aimsExposure to fine particulate matter (PM

methodsBaseline data from 113 Los Angeles Latino adolescents with obesity (discovery cohort) were analyzed, including magnetic resonance imaging-measured hepatic fat fraction (HFF), liver stiffness (LS), and serum metabolomics and lipidomics. Visit-year average exposures to 15 PM

resultsPM

conclusionPM

Indexed as

Air PollutantsEnvironmental ExposureFatty LiverLipaseLiverMembrane ProteinsParticulate MatterAcyltransferasesAdolescentFemaleGenotypeHumansLos AngelesMalePhospholipases A2, Calcium-IndependentAcyltransferasesAir PollutantsLipaseMembrane ProteinsParticulate MatterPhospholipases A2, Calcium-IndependentPNPLA3 protein, humanHepatic steatosisLiver fibrosisMetabolic disordersPM(2.5)compositionVulnerability

Identifiers

PMID42561592
PMCPMC13680008

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.