Evidence map›Paper›PMID 42561305›Full record

SynthesisCoDAS2026

Prevalence and impact of orofacial pain in older adults with dementia: a systematic review and meta-analysis.

Mylena de Abreu Cardoso, Kaliane Rodrigues da Cruz, Rayane Délcia da Silva, Karinna Veríssimo Meira Taveira, José Stechman-Neto, Cristiano Miranda de Araujo, Thalita de Paris Matos Bronholo, Angela Graciela Deliga Schroder

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in CoDAS, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mylena de Abreu CardosoFaculdade de Odontologia, Universidade Tuiuti do Paraná - UTP - Curitiba (PR), Brasil.ORCID http://orcid.org/0009-0008-3482-9905
Kaliane Rodrigues da CruzFaculdade de Odontologia, Universidade Tuiuti do Paraná - UTP - Curitiba (PR), Brasil.ORCID http://orcid.org/0000-0003-3641-4531
Rayane Délcia da SilvaPrograma de Pós-graduação em Odontologia, Universidade Tuiuti do Paraná - UTP - Curitiba (PR), Brasil.ORCID http://orcid.org/0000-0003-1935-6448
Karinna Veríssimo Meira TaveiraDeparmento de Morfologia, Universidade Federal do Rio Grande do Norte - UFRN - Natal (RN), Brasil.ORCID http://orcid.org/0000-0001-6978-4083
José Stechman-NetoFaculdade de Odontologia, Universidade Tuiuti do Paraná - UTP - Curitiba (PR), Brasil.ORCID http://orcid.org/0000-0002-0259-2420
Cristiano Miranda de AraujoFaculdade de Odontologia, Universidade Tuiuti do Paraná - UTP - Curitiba (PR), Brasil.ORCID http://orcid.org/0000-0003-1325-4248
Thalita de Paris Matos BronholoFaculdade de Odontologia, Universidade Tuiuti do Paraná - UTP - Curitiba (PR), Brasil.ORCID http://orcid.org/0000-0003-2974-4743
Angela Graciela Deliga SchroderFaculdade de Odontologia, Universidade Tuiuti do Paraná - UTP - Curitiba (PR), Brasil.ORCID http://orcid.org/0000-0002-1852-8423

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis systematic review and meta-analysis aimed to determine the prevalence and impact of orofacial pain among older adults with dementia. RESEARCH STRATEGIES: Observational studies were retrieved from EMBASE, LILACS, PubMed/MEDLINE, Scopus, Cochrane, Livivo, and Web of Science databases, in addition to gray literature. The search included studies without language or date restrictions. SELECTION CRITERIA: Eligible studies included participants aged 60 years or older with any type of dementia, reporting the presence, frequency, or characteristics of orofacial pain. Case reports, reviews, and experimental animal studies were excluded. DATA ANALYSIS: Data were extracted independently by calibrated reviewers. Meta-analyses were performed using RStudio software, calculating pooled prevalence rates with 95% confidence intervals. Heterogeneity was assessed using the I2 statistic.

resultsThe overall prevalence of orofacial pain among older adults with dementia was 19%, regardless of dementia type. Associated factors included poor oral hygiene, presence of natural dentition, and xerostomia. Communication difficulties, particularly in non-verbal patients, represented the main diagnostic barrier.

conclusionApproximately one in five older adults with dementia experiences orofacial pain, which significantly affects quality of life. However, underdiagnosis remains common due to cognitive and communicative limitations. Improving professional training, multidisciplinary collaboration, and public health strategies focused on oral healthcare in long-term care facilities are essential to enhance pain detection and management.

Indexed as

DementiaFacial PainAgedHumansMiddle AgedPrevalenceQuality of Life

Identifiers

PMID42561305
PMCPMC13440450

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.