Evidence map›Paper›PMID 42560891›Full record

ArticlePLOS digital health2026

Effectiveness of nonclinic-based dual-task training on physical and cognitive functions and activities of daily living in older adults with cognitive decline: A systematic review and meta-analysis.

Jeerati Rattanatreyanupab, Htet Htet Hnin, Theerapol Witthiwej, Vimonwan Hiengkaew, Pagamas Piriyaprasarth, Yasutaka Nikaido, Ammarin Thakkinstian, Kunlawat Thadanipon, Saharat Liampeng, Sunee Bovonsunthonchai

Abstract read
In one paragraph

Article in PLOS digital health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jeerati RattanatreyanupabFaculty of Physical Therapy, Mahidol University, Nakhon Pathom, Thailand.
Htet Htet HninFaculty of Physical Therapy, Mahidol University, Nakhon Pathom, Thailand.
Theerapol WitthiwejDivision of Neurosurgery, Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Vimonwan HiengkaewFaculty of Physical Therapy, Mahidol University, Nakhon Pathom, Thailand.
Pagamas PiriyaprasarthFaculty of Physical Therapy, Mahidol University, Nakhon Pathom, Thailand.
Yasutaka NikaidoClinical Department of Rehabilitation, Osaka Medical and Pharmaceutical University Hospital, Osaka, Japan.
Ammarin ThakkinstianDepartment of Clinical Epidemiology and Biostatistics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Kunlawat ThadaniponDepartment of Clinical Epidemiology and Biostatistics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Saharat LiampengDepartment of Clinical Epidemiology and Biostatistics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Sunee BovonsunthonchaiFaculty of Physical Therapy, Mahidol University, Nakhon Pathom, Thailand.ORCID https://orcid.org/0000-0003-1044-3174

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Older adults with cognitive decline commonly demonstrate deficits in memory, attention, and problem-solving, leading to reduced ability to perform activities of daily living (ADL). Nonclinic-based dual-task training (DTT), delivered at home, in community, or via telerehabilitation, aligns with digital health strategies to improve accessibility and continuity of care for older adults with cognitive decline. This review examined the effects of such intervention on gait, functional mobility, cognitive performance, and ADL, as well as adverse events, feasibility, acceptability, and caregiver burden. Six electronic databases, including PubMed, Embase, CINAHL, CENTRAL, IEEE Xplore, and ProQuest, were systematically searched. Eligible studies were randomized controlled trials (RCTs) investigating the effectiveness of nonclinic-based DTT on variables in older adults with cognitive decline. The risk of bias was assessed using the revised Cochrane risk-of-bias tool for randomized trials version 2 (RoB 2). Data were synthesized using pairwise meta-analysis to compare the DTT with active or passive controls, and network meta-analysis to compare and rank treatment approaches. Twenty-three RCTs involving 1,674 participants were included. The DTT demonstrated significantly greater improvements than the active control in functional mobility (SMD = 0.49; 95% CI, 0.08-0.89; p = 0.019) and global cognition (SMD = 0.32; 95% CI, 0.10-0.55; p = 0.005). Compared with the passive control, the DTT also showed greater gains in gait speed (USMD = 0.05 m/s; 95% CI, 0.02-0.08; p = 0.001) and global cognition (SMD = 0.80; 95% CI, 0.37-1.23; p < 0.001). Only minimal adverse effects were reported, while the mean adherence rate across studies was 80.82%, despite identified barriers including technical difficulties, lack of motivation, and caregiver burden. These findings support its feasibility and effectiveness as a complementary approach to conventional interventions, offering a practical alternative that may reduce the reliance on frequent clinic visits and facilitate greater functional independence.

Identifiers

PMID42560891
PMCPMC13446693

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.