Evidence map›Paper›PMID 42560515›Full record

ReviewEuropean child & adolescent psychiatry2026

Effects of insomnia-focused psychological and behavioral interventions on depressive symptoms in children and adolescents: a systematic review and meta-analysis.

Britta Galling, Jiamiao Wu, Amelie Oberstadt, Alexander Dück, Le Xiao, Alexander Prehn-Kristensen, Dirk Lehr

Abstract readReview
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In one paragraph

Review in European child & adolescent psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Britta GallingInstitute for Child and Adolescent Psychiatry, Center of Integrative Psychiatry GmbH, Christian-Albrecht University Kiel, Kiel, Germany. britta.galling@haw-hamburg.de.ORCID http://orcid.org/0000-0002-4390-0207
Jiamiao WuKey Laboratory of Intelligent Drug Research and Development for Mental Disorders, Beijing Anding Hospital, National Clinical Research Center for Mental Disorders, National Center for Mental Disorders, Capital Medical University, Beijing, China.ORCID http://orcid.org/0009-0004-3076-9088
Amelie OberstadtDepartment of Psychology, Faculty of Human Sciences, MSH Medical School Hamburg - University of Applied Sciences and Medical University, Hamburg, Germany.ORCID http://orcid.org/0009-0003-8488-4244
Alexander DückDepartment of Child and Adolescent Psychiatry and Neurology of Rostock, University Medical Center, Rostock, Germany.ORCID http://orcid.org/0000-0002-5925-1942
Le XiaoKey Laboratory of Intelligent Drug Research and Development for Mental Disorders, Beijing Anding Hospital, National Clinical Research Center for Mental Disorders, National Center for Mental Disorders, Capital Medical University, Beijing, China.ORCID http://orcid.org/0000-0003-4323-036X
Alexander Prehn-KristensenInstitute for Child and Adolescent Psychiatry, Center of Integrative Psychiatry GmbH, Christian-Albrecht University Kiel, Kiel, Germany.ORCID http://orcid.org/0000-0002-3510-9888
Dirk LehrDepartment of Health Psychology and Applied Biological Psychology, Faculty of Sustainability, Leuphana University, Lüneburg, Germany.ORCID http://orcid.org/0000-0002-5560-3605

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psychological and behavioral interventions for insomnia are increasingly recognized as promising approaches not only to improve sleep but also to influence mental health outcomes in children and adolescents. This systematic review and meta-analysis examined the effects of insomnia-focused psychological and behavioral interventions on depressive symptoms, with particular attention to potential across selective and indicated prevention as well as adjunctive treatment contexts. A comprehensive literature search was conducted in PubMed/MEDLINE, PsycINFO, the Cochrane Library, and major Chinese databases (CNKI, Wanfang) from inception to December 30, 2025. Randomized controlled trials comparing psychological or behavioral insomnia interventions with control conditions and reporting changes in depressive symptoms in children and adolescents were included. Random-effects meta-analyses, meta-regression analyses, and within-arm standardized mean change analyses were performed. Eight studies comprising 904 participants (mean age=13.46 years) were identified. Across all studies, depressive symptoms improved from baseline to post-intervention, with a significant overall benefit of insomnia-focused interventions compared with control conditions (SMD=0.238, 95% CI=0.088-0.387, p=0.0019). Within-arm analyses indicated that effects in passive-comparator studies reflected genuine intervention benefit rather than spontaneous remission. Subgroup analyses showed no significant moderation by delivery format or setting, including digital interventions. The high intervention completion rate across trials (87%) supports the potential of insomnia as an indirect, less-stigmatizing entry point for depression prevention in children and adolescents - consistent with frameworks proposing that targeting comorbid, causally linked conditions may reduce depressive symptoms while lowering barriers to engagement. Integrating evidence-based insomnia interventions into clinical, school-based, and digital settings could substantially extend the reach of early mental health strategies.

Indexed as

CBT-IChildren and adolescentsDepressionDigital healthMeta-analysisPreventionSleep disorders

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.