ReviewCurrent opinion in nephrology and hypertension2026
Are noninvasive measurements of nephron number achievable in humans?
Review in Current opinion in nephrology and hypertension, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
purpose of the reviewThis review summarizes recent pivotal studies demonstrating the importance of nephron number as a potential clinical marker of kidney health, and highlights technological advances aimed at facilitating the clinical measurement of nephron number in vivo in individuals. Finally, we summarize clinical applications in which measurements of nephron number will likely lead to improved patient care, and discuss challenges to the deployment of technologies to measure nephron number in humans. RECENT
findingsRecent studies have demonstrated that nephron number is an important determinant of risk of kidney disease, and that it can be used to predict outcomes in large patient cohorts. However, there are currently no clinical tools to measure nephron number noninvasively in humans. Several new technologies have now demonstrated that nephron number can be measured in vivo . With further development, these technologies have the strong potential for translation to general use in humans, suggesting that clinical measurements of nephron number will be available in the near future. SUMMARY: New technologies are now emerging that are likely to enable the noninvasive measurement of nephron number in humans. These technologies are supported by a growing understanding of the importance of nephron number in kidney health and risk of kidney disease.
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