Evidence map›Paper›PMID 42559611›Full record

ArticleSensors and actuators. B, Chemical2026

Extended Foreign Body Mitigation for Glucose Biosensors via Tertiary

Mikaylin E Nogler, Rajnish Kumar, Luc Morgan, Casimir J Schaefer, Heba El-Ahmad, Simon J Reinhard, Tsian D Ramrattan, Samantha L Picciotti, Shannon M Wallet, Timothy C Nichols and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Sensors and actuators. B, Chemical, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mikaylin E NoglerDepartment of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.
Rajnish KumarDepartment of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.
Luc MorganDepartment of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.
Casimir J SchaeferDepartment of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.
Heba El-AhmadDepartment of Oral Biology, College of Dentistry, University of Florida, Gainesville, Florida 32610, United States.
Simon J ReinhardDepartment of Oral Biology, College of Dentistry, University of Florida, Gainesville, Florida 32610, United States.
Tsian D RamrattanDepartment of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.
Samantha L PicciottiDepartment of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.
Shannon M WalletDepartment of Oral Biology, College of Dentistry, University of Florida, Gainesville, Florida 32610, United States.
Timothy C NicholsDepartment of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.
Mark H SchoenfischDepartment of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.

Funding

Role of diabetes and nitric oxide release duration on analytical performance of in vivo glucose biosensorsR01DK108318 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SCHOENFISCH, MARK H · 2016 to 2023
$4.5M
NIDDK NIH HHS R01 DK108318
6 · The paper itself

Abstract

The foreign body response (FBR) limits continuous glucose monitor longevity to 10 - 15 d because of chronic inflammation and collagen capsule formation surrounding the implant site. Nitric oxide (NO), a multifunctional bioactive molecule, has previously demonstrated potent FBR mitigation abilities. Here we evaluated the impact of polyurethane sensor membranes doped with a range of NO-release profiles achieved by primary and tertiary

Indexed as

diabetesforeign body responseglucose biosensornitric oxidetertiary S-nitrosothiol

Identifiers

PMID42559611
PMCPMC13441414

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.