Evidence map›Paper›PMID 42559485›Full record

ArticleSSM. Mental health2026

Suicidal thoughts and behaviours in Cape Town: A cross-sectional study of prevalence and social, contextual, and clinical correlates.

Mpho R Tlali, Reshma Kassanjee, Leigh L van den Heuvel, Stephan Rabie, John Joska, Catherine Orrell, Soraya Seedat, Hans Prozesky, Kristina Adorjan, Mary-Ann Davies and 2 more

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Article in SSM. Mental health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Mpho R TlaliCentre for Integrated Data & Epidemiological Research, School of Public Health, University of Cape Town, South Africa.ORCID 0000-0003-0283-2022
Reshma KassanjeeCentre for Integrated Data & Epidemiological Research, School of Public Health, University of Cape Town, South Africa.
Leigh L van den HeuvelDepartment of Psychiatry, Stellenbosch University, South Africa.
Stephan RabieHIV Mental Health Research Unit, Department of Psychiatry and Mental Health, University of Cape Town, South Africa.
John JoskaHIV Mental Health Research Unit, Department of Psychiatry and Mental Health, University of Cape Town, South Africa.
Catherine OrrellDesmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, South Africa.
Soraya SeedatDepartment of Psychiatry, Stellenbosch University, South Africa.
Hans ProzeskyDivision of Infectious Diseases, Department of Medicine, Stellenbosch University and Tygerberg Academic Hospital, Cape Town, South Africa.
Kristina AdorjanDepartment of Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland.
Mary-Ann DaviesCentre for Integrated Data & Epidemiological Research, School of Public Health, University of Cape Town, South Africa.
Leigh F JohnsonCentre for Integrated Data & Epidemiological Research, School of Public Health, University of Cape Town, South Africa.
Andreas D HaasCentre for Integrated Data & Epidemiological Research, School of Public Health, University of Cape Town, South Africa.

Funding

Observational Antiretroviral Studies In Southern Africa (OASIS) CollaborationU01AI069924 · NIAID · UNIVERSITAT BERN · PI Cleophas Chimbetete, Mary-Ann Davies · 2006 to 2026
$55.9M
NIAID NIH HHS U01 AI069924
6 · The paper itself

Abstract

Background: Suicidal thoughts and behaviours (STBs) are traditionally attributed to mental disorders; however, increasing evidence indicates that social determinants contribute to suicide risk. We examined STBs and their socioeconomic, psychosocial and clinical correlates in two communities in Cape Town. Methods: We conducted psychiatric diagnostic interviews (MINI) at three public-sector facilities (2023-2024). Adults aged ≥18 years, with and without HIV, were recruited in a 2:1 ratio. We examined associations between suicidal ideation and sociodemographic factors, violence exposure, perceived stress, mental disorders, and HIV, reporting average marginal effects (AME) as percentage-point differences in predicted probability. Results: We enrolled 613 participants (63.9% female; 65.4% living with HIV; median age 39). The prevalence of past 30-day suicidal ideation was 14.0%, while 22.2% reported a lifetime suicide attempt. Suicidal ideation was more likely among females (8.52 percentage points, 95% CI 3.08 -13.96), those reporting violence in the community (7.52, 0.87 -14.17) or in the family (14.09, 4.56 -23.62), those with moderate (7.76, 2.76 -12.77) or high perceived stress (33.58, 20.67 -46.50), and those with depression (27.13, 14.67 -39.58), post-traumatic stress disorder (27.98, 12.12 -43.84), or alcohol use disorder (8.34, 1.53 -15.15). Associations with high perceived stress and community violence persisted after adjustment for mental disorders. HIV status and other sociodemographic factors showed no evidence of association. Conclusion: STB prevalence was high in peri-urban communities in Cape Town and strongly associated with mental disorders, violence exposure, and perceived stress. These findings underscore the role of structural and psychosocial stressors in shaping suicide risk in low-income communities.

Indexed as

HIVMental disordersSouth AfricaSuicidal ideationSuicide attemptViolence

Identifiers

PMID42559485
PMCPMC13441158

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.