Evidence map›Paper›PMID 42559221›Full record

ArticleChemical science2026

Bioinspired pore engineering in two-dimensional covalent organic frameworks.

Niyati Arora, Jessica Arcudia, Chamila S Bandara, Katarzyna H Drewniak, Sumon Chakrabarty, Rebecca M Johnson, Noora Al-Kharji, G Andrés Cisneros, Ronald A Smaldone

Abstract read
In one paragraph

Article in Chemical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Niyati AroraDepartment of Chemistry and Biochemistry, University of Texas, Dallas 800 W. Campbell Rd Richardson Texas 75080 USA ronald.smaldone@utdallas.edu andres@utdallas.edu.
Jessica ArcudiaDepartment of Physics, University of Texas, Dallas 800 W. Campbell Rd Richardson Texas 75080 USA.
Chamila S BandaraDepartment of Chemistry and Biochemistry, University of Texas, Dallas 800 W. Campbell Rd Richardson Texas 75080 USA ronald.smaldone@utdallas.edu andres@utdallas.edu.
Katarzyna H DrewniakDepartment of Chemistry and Biochemistry, University of Texas, Dallas 800 W. Campbell Rd Richardson Texas 75080 USA ronald.smaldone@utdallas.edu andres@utdallas.edu.
Sumon ChakrabartyDepartment of Chemistry and Biochemistry, University of Texas, Dallas 800 W. Campbell Rd Richardson Texas 75080 USA ronald.smaldone@utdallas.edu andres@utdallas.edu.
Rebecca M JohnsonDepartment of Chemistry and Biochemistry, University of Texas, Dallas 800 W. Campbell Rd Richardson Texas 75080 USA ronald.smaldone@utdallas.edu andres@utdallas.edu.
Noora Al-KharjiDepartment of Chemistry and Biochemistry, University of Texas, Dallas 800 W. Campbell Rd Richardson Texas 75080 USA ronald.smaldone@utdallas.edu andres@utdallas.edu.
G Andrés CisnerosDepartment of Chemistry and Biochemistry, University of Texas, Dallas 800 W. Campbell Rd Richardson Texas 75080 USA ronald.smaldone@utdallas.edu andres@utdallas.edu.ORCID https://orcid.org/0000-0001-6629-3430
Ronald A SmaldoneDepartment of Chemistry and Biochemistry, University of Texas, Dallas 800 W. Campbell Rd Richardson Texas 75080 USA ronald.smaldone@utdallas.edu andres@utdallas.edu.ORCID https://orcid.org/0000-0003-4560-7079

Funding

Computational Simulations of DNA Transaction Enzymes - Application and DevelopmentR35GM151951 · NIGMS · UNIVERSITY OF TEXAS DALLAS · PI Gerardo Andres Cisneros · 2024 to 2026
$1.2M
NIGMS NIH HHS R35 GM151951
6 · The paper itself

Abstract

Covalent organic frameworks (COFs) are permanently porous, molecularly engineered scaffolds that exemplify the intersection of design, chemistry, and function. They are composed of organic monomers stitched together by covalent bonds into highly ordered two- or three-dimensional architectures. The majority of the studies on two dimensional COFs have focused on eclipsed rather than antiparallel stacked structures. Drawing inspiration from non-covalent bonding motifs in biomolecules, we report the design and synthesis of robust two-dimensional (2D) COFs with amide side chains called aCOFamide-1 and -2, which mimic the hydrogen bonding motifs found in β-sheets. These linker-based sidechains adopt an antiparallel stacked configuration to create binding sites that display excellent iodine adsorption capability (5.9 g g

Identifiers

PMID42559221
PMCPMC13439742

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.