ArticleFrontiers in veterinary science2026
Species-aware interpretation of vancomycin-related genomic signals in poultry-derived
Article in Frontiers in veterinary science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Poultry-associated enterococci are relevant to One Health surveillance, yet interpreting vancomycin-related genomic signals requires careful consideration of species biology and detection confidence. Methods: We analyzed broth microdilution MIC data for 218 poultry-origin Results: In the final dataset, no confirmed vancomycin MIC value exceeded 4 μg/ml. Resistome screening of the 73 genomes (CARD-based output) yielded 1,448 resistance-associated annotations (181 unique gene calls; median 12 per genome) and did not detect canonical acquired van operons consistent with Conclusions: These results support a surveillance-grade workflow that anchors van-related genomic reporting to confirmatory phenotyping, genome-confirmed species assignment, and confidence-aware locus inspection to minimize false alarms and improve One Health interpretability.
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