Evidence map›Paper›PMID 42559116›Full record

ArticleCase reports in dentistry2026

Bilateral Lower Lip Swelling as an Early Manifestation of Crohn's Disease in a 16-Year-Old Patient: A Case Report.

Milica Stojicevic, Alexander Benz, Andrea Kreienbühl, Mometo Ali Mao Aweys, Fabienne Andrina Bosshard

Abstract read
In one paragraph

Article in Case reports in dentistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Milica StojicevicClinic of Oral Surgery, Center for Dental Medicine, University of Zurich, Zurich, Switzerland, uzh.ch.ORCID https://orcid.org/0009-0005-6787-9974
Alexander BenzHistological Diagnostic AG Kempf und Pfalz, Zurich, Switzerland.
Andrea KreienbühlDepartment of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, usz.ch.ORCID https://orcid.org/0009-0002-3564-639X
Mometo Ali Mao AweysClinic of Oral Surgery, Center for Dental Medicine, University of Zurich, Zurich, Switzerland, uzh.ch.
Fabienne Andrina BosshardClinic of Oral Surgery, Center for Dental Medicine, University of Zurich, Zurich, Switzerland, uzh.ch.ORCID https://orcid.org/0000-0002-6020-6073

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Crohn's disease and ulcerative colitis are chronic inflammatory bowel diseases that are often diagnosed with a significant delay. Although Crohn's disease can affect the entire gastrointestinal tract-from the mouth to the anus-ulcerative colitis is limited to the colon and rectum. This report describes the case of a 16-year-old male patient who suffered from a painless, bilateral swelling of the lower lip persisting for 4 months. Elevated fecal calprotectin (510 mg/kg) and subsequent endoscopic examination confirmed the diagnosis of Crohn's disease. Immunosuppressive therapy led to full resolution of the lip swelling and overall clinical improvement. Oral manifestations such as ulcers, gingivitis, and angular cheilitis can be the first signs of a systemic disease, such as Crohn's disease in this case, and therefore provide an opportunity for early detection by general dentists.

Indexed as

case reportgranulomatous cheilitisoral manifestationoral medicineswelling

Identifiers

PMID42559116
PMCPMC13439983

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.