Evidence map›Paper›PMID 42559074›Full record

ArticleNagoya journal of medical science2026

Sestrin2 alleviates age-related hearing loss through mediating PINK1/Parkin related mitophagy.

Liwen Wang, Yuenong Jiao, Tianqi Nie, Linlan Jiang, Shuyi Gao, Jinyu Wang

Abstract read
In one paragraph

Article in Nagoya journal of medical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Liwen WangDepartment of Otorhinolaryngology Head and Neck Surgery, Guangzhou Twelfth People's Hospital, Guangzhou, China.
Yuenong JiaoDepartment of Otorhinolaryngology Head and Neck Surgery, Guangzhou Twelfth People's Hospital, Guangzhou, China.
Tianqi NieDepartment of Otorhinolaryngology Head and Neck Surgery, Guangzhou Twelfth People's Hospital, Guangzhou, China.
Linlan JiangDepartment of Otorhinolaryngology Head and Neck Surgery, Guangzhou Twelfth People's Hospital, Guangzhou, China.
Shuyi GaoDepartment of Otorhinolaryngology Head and Neck Surgery, Guangzhou Twelfth People's Hospital, Guangzhou, China.
Jinyu WangDepartment of Otorhinolaryngology Head and Neck Surgery, Guangzhou Twelfth People's Hospital, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Age-related hearing loss (ARHL) is closely linked to mitochondrial dysfunction in cochlear hair cells; however, its molecular regulation remains unclear.

Indexed as

Hearing LossMitophagyNuclear ProteinsProtein KinasesUbiquitin-Protein LigasesAgingAnimalsApoptosisHair Cells, AuditoryMembrane Potential, MitochondrialMiceMice, KnockoutMitochondriaOxidative StressPTEN-Induced Putative KinaseSestrinsNuclear Proteinsparkin proteinProtein KinasesPTEN-Induced Putative KinaseSesn2 protein, mouseSestrinsUbiquitin-Protein Ligasesage-related hearing lossmitochondrial functionmitophagySESN2Sestrin2

Identifiers

PMID42559074
PMCPMC13438742

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.