ArticleDEN open2027
Lidocaine Spray Versus Viscous Lidocaine Solution Plus Lidocaine Spray in Patients Undergoing Non-Sedated Esophagogastroduodenoscopy: A Randomized Controlled Trial.
Article in DEN open, 2027. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06185933 (Lidocaine Spray vs Viscous Lidocaine Solution Plus Lidocaine Spray in Patients Undergoing Non-Sedated Esophagogastroduodenoscopy), which is not on this map. Not yet cited in PubMed.
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Lidocaine Spray vs Viscous Lidocaine Solution Plus Lidocaine Spray in Patients Undergoing Non-Sedated Esophagogastroduodenoscopy: A Randomized Controlled Trial
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Authors and funding
4 authors.
Funding
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Abstract
Background: Non-sedated esophagogastroduodenoscopy (EGD) is preferred in patients at risk from sedatives. However, achieving effective pharyngeal anesthesia remains a challenge. This study compared lidocaine spray alone with a combination of lidocaine spray and viscous lidocaine solution. Methods: This single-center, randomized controlled trial was conducted between January 2024 and October 2024 at Sawanpracharak Hospital, Thailand. A total of 250 patients undergoing non-sedated EGD were randomized to receive lidocaine spray alone (S group, Results: Baseline characteristics were comparable between groups. The S + V group reported significantly lower procedural pain than the S group (mean VAS 1.6 ± 1.1 vs. 3.1 ± 1.7; Conclusion: Combining lidocaine spray with viscous lidocaine solution significantly reduced procedural discomfort and improved procedural conditions during non-sedated EGD compared with lidocaine spray alone. Trial Registration: ClinicalTrials.gov identifier: NCT06185933.
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