ArticleHealth science reports2026
Antimicrobial Resistance at the Human-Animal-Environment Interface: A One Health Perspective on Drivers, Transmission, and Public Health Responses.
Article in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Antimicrobial resistance (AMR) is a global health threat driven by interconnected antimicrobial use and environmental pressures across human, animal, and ecological systems. This review synthesizes current evidence on the major drivers, transmission pathways, reservoirs, surveillance challenges, and public health responses associated with AMR at the human-animal-environment interface. Methods: Relevant literature published up to March 2026 was identified through searches of PubMed, Scopus, Web of Science, and Google Scholar using terms related to AMR, One Health, antimicrobial use, transmission, surveillance, and public health responses. Peer-reviewed studies, systematic reviews, and reliable reports were considered, while duplicate, unrelated, non-English, and non-peer-reviewed publications were excluded. Results: AMR is driven by inappropriate antimicrobial use in human healthcare, livestock and aquaculture production, and environmental contamination from wastewater, agricultural runoff, and pharmaceutical discharges. Resistant organisms and antimicrobial resistance genes circulate across sectors through food, water, direct contact, occupational exposure, wildlife, and horizontal gene transfer. Major gaps remain in integrated surveillance, cross-sector data sharing, diagnostic capacity, laboratory infrastructure, and implementation, particularly in resource-limited settings. These challenges are compounded by fragmented governance, inadequate regulation, limited stewardship, and poor coordination among human, animal, and environmental health sectors, hindering effective AMR prevention and control. Conclusions: Containing AMR requires coordinated One Health action integrating antimicrobial stewardship, infection prevention, improved diagnostics, harmonized surveillance, environmental monitoring, and cross-sector data sharing. Strengthening implementation capacity and equitable collaboration is essential for effective and sustainable AMR control.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.