Evidence map›Paper›PMID 42558953›Full record

ReviewJournal of clinical and translational hepatology2026

Advances in Precise Assessment of Portal Pressure in Porto-sinusoidal Vascular Disease.

Kun Zhu, Qingchun Fu, Muyun Liu

Abstract readReview
In one paragraph

Review in Journal of clinical and translational hepatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kun ZhuDepartment of Infectious Disease, 905 Hospital of PLA Navy Affiliated to Naval Medical University, Shanghai, China.
Qingchun FuClinical Research Center for Liver Diseases, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0002-7217-5315
Muyun LiuDepartment of Infectious Disease, 905 Hospital of PLA Navy Affiliated to Naval Medical University, Shanghai, China.ORCID https://orcid.org/0000-0003-0733-3150

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Porto-sinusoidal vascular disease (PSVD) is a non-cirrhotic vascular liver disorder characterized by portal and sinusoidal microvascular lesions and is frequently complicated by portal hypertension. Accurate assessment of portal pressure is essential for diagnosis, risk stratification, therapeutic decision-making, and prognostic evaluation in PSVD. However, unlike cirrhosis, portal hypertension in PSVD is predominantly presinusoidal, making hepatic venous pressure gradient measurement prone to underestimating true portal pressure. Recent advances have promoted a transition from conventional invasive assessment toward a multimodal and precision-oriented strategy integrating non-invasive and minimally invasive techniques. Ultrasound elastography, computed tomography, and magnetic resonance imaging-particularly radiomics-based approaches-provide valuable tools for differentiating PSVD from cirrhosis and estimating the severity of portal hypertension. Endoscopic ultrasound-guided portal pressure gradient measurement has emerged as a promising minimally invasive technique for direct hemodynamic assessment and prognostic stratification. In addition, laboratory biomarkers, digital modeling, and artificial intelligence-assisted analysis may further improve individualized risk prediction and dynamic monitoring. This review summarizes current advances in portal pressure assessment in PSVD, critically discusses the strengths and limitations of existing approaches, and highlights future directions toward non-invasive, digital, and precision-guided management.

Indexed as

Artificial intelligenceElastographyEndoscopic ultrasoundHepatic venous pressure gradientPortal hypertensionPortal pressure assessmentPorto-sinusoidal vascular diseaseRadiomics

Identifiers

PMID42558953
PMCPMC13439104

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.