SynthesisFrontiers in parasitology2026
Diagnostic accuracy of rapid and point-of-care tests for
Synthesis in Frontiers in parasitology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
- Erratum issued
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Accurate and accessible point-of-care testing for urogenital schistosomiasis (UGS) is vital for control and prevention in sub-Saharan Africa. Point-of-care (POC) rapid diagnostic tests with high sensitivity for both high and low parasite burdens have been developed. These tests need to be assessed for their applicability in poorly resourced UGS-endemic areas so that control programs can be initiated, and improved screening and routine diagnosis can be implemented. Methods: This diagnostic test accuracy (DTA) review evaluates the sensitivity and specificity of eligible field-based index tests compared to laboratory-based reference tests for the diagnosis of UGS among individuals from Africa. Four databases were systematically searched for DTA studies on Results: Twenty-nine studies were evaluated, in which nine different POC and rapid tests were eligible, and four were included in a meta-analysis. Two field-based molecular tests, loop-mediated isothermal amplification (LAMP) and recombinase polymerase amplification (RPA), demonstrated high accuracy (sensitivity, 94.7%; specificity, 66.4%; and sensitivity, 94.1%; specificity, 96.6%, respectively). The immunochromatographic-rapid diagnostic test (ICT-RDT) and Conclusion: Further validation with improved reference standards is required to assess the diagnostic accuracy of many of the tests identified. RPA and LAMP emerged as promising field-applicable rapid tests for schistosomiasis control.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.